Skip to content

Research

Fellows have opportunities to learn and get involved in both clinical and basic science research. They can do research with the faculty inside and outside of the division of neonatology. The research interests of the faculty vary from basic science research in infection/ immunology to cerebral circulation and physiology. Varied clinical science projects are also underway and we have been part of several multicenter trials.

The NICU also has a database for the past 30 years which makes it easy for faculty and fellows to obtain background information for clinical projects.

Selected Recent Publications

  1. Davidson, J and Elabiad, MT. A Simple Intervention to Decrease Nutrient Losses in Continuous Feeds with Human Milk, Journal of Pediatric Gastroenterology & Nutrition. 2020 Apr;70(4):e81-e83
  2. Phillip R, Weems MF, Talati AJ, Apalodimas L, Sathanandam SK. The First International PDA Symposium- Memphis, TN, May 18-19, 2018– Proceedings. Congenital Cardiology Today, Feb 2019, Pages 14-16.
  3. Ferguson, J.Pharmacotherapy for Patent Ductus Arteriosus Closure. Congenital Heart Disease. 2019 Jan; 14(1):52-56, doi:10-1111/chd 12715 PMID:305368
  4. Jancelewicz T, Paton EA, Jones J, Weems MF, Lally PA, Langham Jr MR. Risk-Stratification Enables Accurate Single-Center Outcomes Assessment in Congenital Diaphragmatic Hernia (CDH). Journal of Pediatric Surgery. 2019 Jan 31 [Epub ahead of print]. PMID:30792092. DOI:10.1016/j.jpedsurg.2019.01.020.
  5. Herrera O, Talati, AJ, Helms R Plasma Citrulline Concentrations in Neonates with or without Gastrointestinal Disease During Periods of Parenteral and Enteral Nutrition.. JPEN J Parenter Enteral Nutr. 2019 Jun 23. doi: 10.1002/jpen.1671. [Epub ahead of print] PMID:31231843
  6. Talati AJ, Scott TA, Barker B, Grubb PH; Tennessee Initiative for Perinatal Quality Care Golden Hour Project Team. Improving neonatal resuscitation in Tennessee: a large-scale, quality improvement project.J Perinatol. 2019 Dec;39(12):1676-1683. doi: 10.1038/s41372-019-0461-3. Epub 2019 Aug 15.PMID:31417143.
  7. Rana D, Pollard L, Rowland J, Dhanireddy R, Pourcyrous M. Amplitude-integrated EEG in infants with neonatal abstinence syndrome. J Neonatal Perinatal Med. 2019 Jul 22. doi: 10.3233/NPM-1834. [Epub ahead of print] PMID:31356218
  8. Sathanandam S, Agrawal H, Chilakala S, Johnson J, Allen K, Knott-Craig C, Rush Waller B, Philip R. Can transcatheter PDA closure be performed in neonates ≤1000 grams? The Memphis experience. Congenit Heart Dis. 2019 Jan;14(1):79-84. doi: 10.1111/chd.12700. PMID:30811793
  9. Philip R, Nathaniel Johnson J, Naik R, Kimura D, Boston U, Chilakala S, Hendrickson B, Rush Waller B, Sathanandam S Effect of patent ductus arteriosus on pulmonary vascular disease. Congenit Heart Dis. 2019 Jan;14(1):37-41. doi: 10.1111/chd.12702. Review. PMID:30811787
  10. Sathanandam S, Balduf K, Chilakala S, Washington K, Allen K, Knott-Craig C, Rush Waller B, Philip R. Role of Transcatheter patent ductus arteriosus closure in extremely low birth weight infants. Catheter Cardiovasc Interv. 2019 Jan 1;93(1):89-96. doi: 10.1002/ccd.27808. Epub 2018 Sep 30.PMID:30269408
  11. Willis KA, Purvis JH, Myers ED, Aziz MM, Karabayir I, Gomes CK, Peters BM, Akbilgic O, Talati AJ, Pierre JF Fungi form interkingdom microbial communities in the primordial human gut that develop with gestational age. FASEB J. 2019 Nov;33(11):12825-12837. doi: 10.1096/fj.201901436RR. Epub 2019 Aug 31.PMID:31480903
  12. Willis KA, Siefker DT, Aziz MM, White CT, Mussarat N, Gomes CK, Bajwa A, Pierre JF, Cormier SA, Talati AJPerinatal maternal antibiotic exposure augments lung injury in offspring in experimental bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2019 Oct 23. doi: 10.1152/ajplung.00561.2018. [Epub ahead of print]PMID:31644311
  13. Willis KA, Pierre JF, Cormier SA, Talati AJ Mice without a microbiome are partially protected from lung injury by hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2019 Oct 30. doi: 10.1152/ajplung.00433.2019. [Epub ahead of print] PMID:31664852
  14. Weems, M. Online, Anytime. Commentary, Pediatrics in Review, 2019 Oct;40(Suppl 1)33. PMID: 31575694. DOI: 10.1542/pir.2019-40S33
  15. Chilakala S (2019) ‘Delivery room management of a Preterm Infant’. In Giancarlo Mari: Safety Training for Obstetric Emergencies. The OB F.A.S.T Approach. St Louis: Elsevier. p. 9-14.
  16. Willis K*, Gomes C*, Rao P, Micic E, Moran R, Stephenson E, Puchowicz M, Mims T, Al Abdullah Q, Gosain A, Yin D, Talati A, Chang E, Han J, Pierre J. TGR5 Signaling Mitigates Parenteral Nutrition Associated Liver Disease. Am J Physiol Gastrointest Liver Physiol. In Press, Dec 2019 *equal authorship
  17. Jose Duncan, Pranit Chotai, Anna Slagle, Ajay Talati, Eunice Huang and Mauro Schenone (2018): Mode of delivery in pregnancies with gastroschisis according to delivery institution. The Journal of Maternal-Fetal and Neonatal Medicine. DOI: 10.1080/14767058.2018.1450860 PMID:29562799
  18. Mink R, Schwartz A, Carraccio C, High P, Dammann C, McGann KA, Kesselheim J, Herman B; Steering Committee of the Subspecialty Pediatrics Investigator Network (collaborator-Talati) Creating the Subspecialty Pediatrics Investigator Network. J Pediatr. 2018 Jan;192:3-4.e2. doi: 10.1016/j.jpeds.2017.09.079.
  19. Wai KC, Hibbs AM, Steurer MA, Black DM, Asselin, JM, Eichenwald EC, Ballard PL, Ballard RA and Keller RL for the Trial of Late Surfactant (TOLSURF) Study Group. Maternal black race and persistent wheezing illness in former extremely lowly gestational age newborns: secondary analysis of a randomized trial. J Pediatr. 2018 Apr 4. pii: S0022-476(18)30220-8. doi: 10.1016/j.jpeds.2018.02.032. [Epub ahead of print] PMID:29627188
  20. Duncan, Jose; Tobiasz, Ana; Aziz, Michael; Dorsett, Katherine; Thompson, Rebecca ; Bursac, Zoran; Talati, Ajay; Mari, Giancarlo; Schenone, Mauro. Fetal pulmonary artery acceleration/ejection time prognostic accuracy for respiratory complications in preterm prelabor rupture of membranes. The Journal of Maternal-Fetal and Neonatal Medicine (accepted for publication, October 2018
  21. Patel S1, Fedinec AL, Liu J2, Weiss MA3, Pourcyrous M4, Harsono M3, Parfenova H5, Leffler CW2. Hydrogen sulfide mediates the vasodilator effect of endothelin-1 in the cerebral circulation Am J Physiol Heart Circ Physiol. 2018 Sep 28. doi: 10.1152/ajpheart.00451.2018. [Epub ahead of print]
  22. The death knell of inhaled nitric oxide to prevent bronchopulmonary dysplasia?Willis K, Peravali S, Weems M. J Perinatol. 2018 Jun;38(6):633-635. doi: 10.1038/s41372-018-0071-5. Epub 2018 Feb 21. No abstract available. PMID:29467517
  23. Shaken or Stirred? Evaluating the combination of budesonide-surfactant for survival free of bronchopulmonary dysplasia. Willis K, Weems M. Acta Paediatr. 2018 Mar;107(3):540. doi: 10.1111/apa.14127. Epub 2017 Nov 13. No abstract available.PMID:29131394
  24. Survey of ECMO practices for infants with hypoxic ischemic encephalopathy. Weems MF, Upadhyay K, Sandhu HS. J Perinatol. 2018 Sep;38(9):1197-1204. doi: 10.1038/s41372-018-0167-y. Epub 2018 Jul 25. PMID:30046182
  25. Astrocyte-produced carbon monoxide and the carbon monoxide donor CORM-A1 protect against cerebrovascular dysfunction caused by prolonged neonatal asphyxia. Parfenova H, Pourcyrous M, Fedinec AL, Liu J, Basuroy S, Leffler CW.Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H978-H988. doi: 10.1152/ajpheart.00140.2018. Epub 2018 Jul 20.PMID:30028198

Abstracts Presented

  1. Grover, T, MF Weems, B Brozanski, JM Daniel, NE Rintoul, A Walden, HL Hedrick, B Mahmood, RB Seabrook, K Murthy, I Zaniletti, S Keene, B Haberman. Central line utilization and complications in infants with congenital diaphragmatic hernia (CDH). Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:4140.721.
  2. Coleman, C, Z Billimoria, JP Cleary, JM Daniel, TR Grover, SE Hamrick, S Keene, B Mahmood, RB Seabrook, MF Weems, T Najaf, RL Chapman, NE Rintoul, R DiGeronimo, KM Sullivan, DR Dirnberger. ECMO for Neonatal Respiratory Failure in Children’s Hospital NICUs: How small is too small? Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:4136.649.
  3. Billimoria, Z, NE Rintoul, RL Chapman, MF Weems, DR Dirnberger, KM Sullivan, JM Daniel, JP Cleary, S Keene, B Gray, TR Grover, RB Seabrook, T Najaf, R DiGeronimo. Variation in Peri-surgical Anti-coagulation Practices in Congenital Diaphragmatic Hernia Patients on Extracorporeal Membrane Oxygenation. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA. E-PAS2020:2834.581.
  4. DiGeronimo, R, Z Billimoria, NE Rintoul, I Zaniletti, RL Chapman, S Keene, RB Seabrook, DR Dirnberger, SR O’Neill, JP Cleary, TR Grover, JM Daniel, SE Hamrick, B Mahmood, MF Weems, T Najaf, B Gray, KM Sullivan. Morbidity and mortality of neonates with severe meconium aspiration syndrome and ECMO: an analysis from the Children’s Hospital Neonatal Consortium. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA. E-PAS2020:2837.626.
  5. Billimoria, Z, R DiGeronimo, B Gray, RL Chapman, MF Weems, DR Dirnberger, JM Daniel, JP Cleary, S Keene, SE Hamrick, TR Grover, RB Seabrook, T Najaf, KM Sullivan, NE Rintoul. Variation in Surgical Practices in Congenital Diaphragmatic Hernia Patients on Extracorporeal Membrane Oxygenation. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA. E-PAS2020:1414.198.
  6. Chilakala S, Upadhyay K, Phillip R, Bugnitz M, Lee, Talati AJ. Trends of Neonatal Resuscitation in NICU and various Intensive Care Units. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:1431.519.
  7. Upadhyay K, Guimera D, Hysmith N, Talati AJ. Infection prevention and control of gram-negative organisms in NICU. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:1406.86
  8. Gruver MD, Skeen A, Dhanireddy R. Maternal Expressed Breast Milk vs. Donor Breast Milk as the First Feed on Clinical Outcomes in Extremely Low Birth Weight Infants. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:1436.613.
  9. Key L, Purvis J, Taylor S, Talati AJ. Breast is B.E.S.T. Breastfeeding improvement through resident Education and Sustainability Teaching. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:2825.403
  10. Pourcyrous M, Rana D, Elabiad M, Gaston K, DeBaer L, Dhanireddy R. African American (AA) Neonates Have a Lower Risk of Developing Neonatal Opioid Withdrawal Syndrome (NOWS) Compared to the Caucasians (CA). Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:2836.603
  11. Pourcyrous M, Rana D, Gaston K, Dhanireddy R. The Occurrence of Neonatal Opioid Withdrawal Syndrome (NOWS) in Neonates Born to Mothers with Sickle Cell Disease (SCD). Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:2836.604
  12. Bang A, Jain M, Payalmesh, Karuna, Anupitihas, Swapnilkolhe, Drvikramdatta, Drmahtab, Dhanireddy R. Reduction of Hypothermia at One Hour of Life in Neonates Born at a Teaching Public Hospital in Rural Central India. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:2841.674
  13. Jain M, Bang A, Prachigawande, Pushpanjalikamble, Payalmesh, Dhanirreddy R. Institution of an Antibiotic Stewardship Program in the NICU of a Teaching Public Hospital in Rural Central India. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:2842.695
  14. Talati AJ (Moderator). Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:3370
  15. Bang A, Jain M, Chauhan V, Jategaonkar S, Dhanireddy R. Improving Neonatal Outcomes Through Multidisciplinary Quality Improvement Initiatives in a Teaching Public Hospital in Rural Central India. Platform presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:3345.6
  16. Key L, Swindall PK, Desai J, Gaston K, Talati AJ. The Danger in Diazoxide. Platform presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:3780.8
  17. Willis K, Banks, White, Grezonzew, Talati AJ, Pierre, Clal s K. Fungal Airway Microbiome at Birth. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:3930.539
  18. Irwin C, Key L, Desai J, Talati AJ. Are you my mother? Donor milk vs. Mother's milk in the NICU: A Prospective Cohort Study. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:3924.412
  19. Borcky T, Desai J, Brown, T, Talati AJ, Upadhyay K, Effect of multimodal stimulation with live music therapy on preterm infants in NICU. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:4134.600.
  20. Konjeti M, Shah K, Upadhyay K, Talati AJ. The Characteristics of Coombs Positive Infants with Hyperbilirubinemia. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:4140.721.
  21. Jain M, Bang A, Peshram P, Kawhale K, Itihas A, Kolhe S, Datta V, Singh M, Dhanirreddy R. Improvement in Initiation of Breastfeeding Within an Hour After Birth at a Teaching Public Hospital in Rural Central India. Poster presentation at Pediatric Academic Societies Annual Meeting, Philadelphia, PA, May 5, 2020. E-PAS2020:4140.721.
  22. Boyle C, Davidson JM and Talati AJ, Screening Asymptomatic Infants Born to Mothers with HHSV Lesion: Is Less More? (Trainee Travel Award Winner); Southern Society for Pediatric Research Annual Conference, New Orleans, LA, February 13-15, 2020
  23. Davidson JM, A Donahue A, and Pivnick E, Adams-Oliver Syndrome: Is It on Your Differential Diagnosis for Cutis Aplasia? Southern Society for Pediatric Research Annual Conference, New Orleans, LA, February 13-15, 2020
  24. Nair SS, Sathanandam SK, Harvey EM, Chilakala SK, Apalodimas L, and Philip R; Comparison of Low Cardiac Output Syndrome After Transcatheter PDA Closure and Surgical PDA Ligation in Extremely Low Birth Weight Infants. Southern Society for Pediatric Research Annual Conference, New Orleans, LA, February 13-15, 2020
  25. Willis K, Pierre J, Cormier S, Talati AJ. Maternal Peripartum Antibiotic Exposure Worsens Experimental Bronchopulmonary Dysplasia. Platform presentation at AAP NCE – SONPM, Orlando, FL, November 2018

Last Published: Jul 24, 2020