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Laboratory-Based Research

Dr. Dale directs an active research laboratory in the Coleman College of Medicine Building. The research activities are directed at understanding the basic mechanisms of group A streptococcal infections and their complications. This includes structure/function studies of streptococcal virulence determinants, normal and abnormal host immune responses to streptococcal antigens, the pathogenesis of acute rheumatic fever and rheumatic carditis, and the development of vaccines that will prevent group A streptococcal infections. Infectious disease fellows may opt to spend an extended period of time working in the laboratory as an integral member of the research team.

Clinical Research

Several members of the ID faculty also conduct clinical research projects, many of which are focused on improving the delivery of care for people living with HIV. Most of the research is conducted in the Adult Special Care Clinic, the region’s largest Ryan White funded clinic serving this population. Additional clinical research projects involving phase 3 and phase 4 assessments of therapeutics for infectious diseases are conducted at Methodist University Hospital and the VA Medical Center. Interested infectious disease fellows are encouraged to work with faculty in designing a clinical research question and carrying out a mentored research project with the goal of presenting their work at a national meeting.

Last Published: Mar 12, 2021