Bob M. Moore II, Ph.D.

Bob M. Moore II, Ph.D.

Professor


Department of Pharmaceutical Sciences


The University of Tennessee Health Science Center
874 Union Avenue, Room 327D
Memphis, TN 38163
Tel: (901) 448-6085
Fax: (508) 448-6828
Email: Bob M. Moore



Education

  • B.S. in Chemistry, Indiana State University, 1983
  • M.S. in Chemistry, Indiana State University, 1989
  • Ph.D. (Medicinal Chemistry), University of Kansas, 1995

Research Interests

Research in Dr. Moore's lab integrates synthetic organic chemistry, computational chemistry and biological assays aimed at developing new chemotherapeutic entities. The current areas of research include:

  1. Development of cannabinoid receptor (CB1 and CB2) agonist and antagonist.
  2. Development of novel therapies for combat causality care with emphasis on hemorrhagic shock and hemostasis.
  3. Development of GPRC directed anti-neoplastic agents.
  4. Combination drug therapies for the treatment of sepsis, stroke and ischemic brain conditions.

Representative Publications

  • Presley CS, Abidi AH, Moore BM 2nd. Optimization of cAMP fluorescence dataset from ACTOne cannabinoid receptor 1 cell line. Data Brief. 2016 Apr 1;7:1118-23. doi: 10.1016/j.dib.2016.03.086. eCollection 2016 Jun. PubMed PMID: 27115025; PubMed Central PMCID: PMC4833130.
  • Presley CS, Abidi AH, Moore BM 2nd. Corrigendum to 'Cannabinoid receptor 1 ligands revisited: Pharmacological assessment in the ACTOne system' [Analytical Biochemistry 498 (2016) 8-28]. Anal Biochem. 2016 May 15;501:47. doi: 10.1016/j.ab.2016.03.002. Epub 2016 Mar 15. PubMed PMID: 27064120.
  • Moore BM, Baker T. An Exploratory Examination of College Students' Likelihood of Reporting Sexual Assault to Police and University Officials: Results of a Self-Report Survey. J Interpers Violence. 2016 Feb 24. pii: 0886260516632357. [Epub ahead of print] PubMed PMID: 26917571.
  • Presley CS, Abidi AH, Moore BM 2nd. Cannabinoid receptor 1 ligands revisited: Pharmacological assessment in the ACTOne system. Anal Biochem. 2016 Apr 1;498:8-28. doi: 10.1016/j.ab.2015.12.019. Epub 2016 Jan 7. PubMed PMID: 26772161.
  • Harrold I, Carbonneau S, Moore BM, Nguyen G, Anderson NM, Saini AS, Kanki JP, Jette CA, Feng H. Efficient transgenesis mediated by pigmentation rescue in zebrafish. Biotechniques. 2016 Jan 1;60(1):13-20. doi: 10.2144/000114368. eCollection 2016. PubMed PMID: 26757807; PubMed Central PMCID: PMC4768720.
  • Presley CS, Mustafa SM, Abidi AH, Moore BM 2nd. Synthesis and biological evaluation of (3',5'-dichloro-2,6-dihydroxy-biphenyl-4-yl)-aryl/alkyl-methanone selective CB2 inverse agonist. Bioorg Med Chem. 2015 Sep 1;23(17):5390-401. doi: 10.1016/j.bmc.2015.07.057. Epub 2015 Jul 29. PubMed PMID: 26275680.

View more references (pubmed link)