James W. Wheless, M.D.

James W. Wheless, M.D.

Professor and Chief
Department of Pediatric Neurology

Divison of Pediatric Neurology
Le Bonheur Children's Hospital

Le Bonheur Comprehensive Epilepsy Program

Le Bonheur Neuroscience Center

Clinical Director and Chief
Department of Pediatric Neurology
St. Jude Children's Research Hospital

The University of Tennessee Health Science Center
Pediatric Neurology
777 Washington Avenue, Suite 335
Memphis, TN 38105
Phone: (901) 287-5207
Fax: (901) 287-5325
Email: James W. Wheless


  • M.D. Institution: University of Oklahoma, Oklahoma City
  • Residency & Fellowship Training: University of Oklahoma Tulsa Medical College, Tulsa; Child Neurology Fellow, Children's Memorial Hospital, Northwestern University, Chicago; EEG/Epilepsy Fellow, Medical College of Georgia, Augusta

Research Interests

My interests are seizure disorders and epilepsy in children and adolescents. This includes drug therapy, the ketogenic diet, epilepsy surgery, vagus nerve stimulation and magnetoencephalography.

Representative Publications

  • Choudhri AF, Patel RM, Siddiqui A, Whitehead MT, Wheless JW. Cortical Activation Through Passive-Motion Functional MRI. AJNR Am J Neuroradiol. 2015 Jul 30. [Epub ahead of print] PubMed PMID: 26228890.
  • Rivas-Coppola MS, Patterson AL, Morgan R, Wheless JW. Bupropion Overdose Presenting as Status Epilepticus in an Infant. Pediatr Neurol. 2015 Jun 14. pii: S0887-8994(15)00278-7. doi: 10.1016/j.pediatrneurol.2015.05.018. [Epub ahead of print] PubMed PMID: 26183178.
  • Caron E, Wheless CE, Patters AB, Wheless JW. The charges for seizures in the pediatric emergency room: a single center study. Pediatr Neurol. 2015 May;52(5):517-20. doi: 10.1016/j.pediatrneurol.2015.02.010. Epub 2015 Feb 18. PubMed PMID: 25882079.
  • Rentz AM, Skalicky AM, Pashos CL, Liu Z, Magestro M, Pelletier CL, Prestifilippo JA, Nakagawa J, Frost MD, Dunn DW, Wheless JW. Caring for Children With Tuberous Sclerosis Complex: What Is the Physical and Mental Health Impact on Caregivers? J Child Neurol. 2015 Apr 2. pii: 0883073815575364. [Epub ahead of print] PubMed PMID: 25838447.
  • Pellock JM, Wheless JW, Douglass LM. In response: Lennox-Gastaut syndrome may be a curable, reversible epileptic encephalopathy. Epilepsia. 2015 Mar;56(3):500-1. doi: 10.1111/epi.12915. PubMed PMID: 25778756.
  • Rentz AM, Skalicky AM, Liu Z, Wheless JW, Dunn DW, Frost MD, Nakagawa J, Magestro M, Prestifilippo J. Tuberous sclerosis complex: a survey of health care resource use and health burden. Pediatr Neurol. 2015 Apr;52(4):435-41. doi: 10.1016/j.pediatrneurol.2014.11.013. Epub 2014 Nov 29. PubMed PMID: 25771998.

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