Ying Kong, Ph.D.

Ying Kong, Ph.D.

Assistant Professor
858 Madison Ave.
401 Molecular Science Building
Memphis, TN 38163
Email: ykong3@uthsc.edu
Phone: 901-448-2465
Fax: 901-448-7360


Research Interests

Our laboratory is interested in the molecular microbiology and immunology of tuberculosis (TB). TB is an infectious disease mainly caused by Mycobacterium tuberculosis. It remains a leading public health problem worldwide. Our primary goal is to better understand the pathogenesis of this disease. We have developed a variety of non-invasive optical in vivo imaging tools to study TB in animal models. By using non-invasive real-time imaging technologies to monitor TB in small animals, infections can be visualized within individual animals over time, without requiring euthanasia to determine the location and quantity of bacteria. It allows comprehensive examination of all tissues and organs, rather than sampling of sites previously known to be infected, tuberculosis infected animals so it may discover important events that we could neglect using samples from discontinued time points. It helps reducing number of experimental animals by obtaining data from numerous time points without having to sacrificing animals to sample tissues in the middle of observation, and thus reducing the cost. Combining these in vivo imaging tools with other cutting-edge in vitro technologies, we will study host-pathogen interactions in M. tuberculosis infected animals and cell lines to identify bacterial and host factors affecting bacterial infection, survival, persistence, and reactivation. The results from these studies will contribute to development of improved diagnostic tools, anti-tuberculosis therapies and vaccines.

Selected Publications

Education

  • Ph.D. University of Michigan
  • Postdoc: University of Texas Health Science Center Texas A & M Health Science Center