Fu-Ming Zhou, Ph.D.

Fu-Ming Zhou, Ph.D.

Professor
Department of Pharmacology


The University of Tennessee Health Science Center
874 Union Avenue
Memphis, TN 38163
Phone: (901) 448-1779
Lab: 315 Crowe Building
Email: Fu-Ming Zhou

 

Education

  • Ph.D. Institution: Department of Physiology and Biophysics, University of Alabama at Birmingham
  • Postdoctoral: Department of Neurobiology, University of Alabama at Birmingham

Link

Pharmacology - Fu-Ming Zhou

Research Interests

Dr. Zhou currently conducts a multidisciplinary research program designed to determine the molecular, cellular and neuropharmacological mechanisms of the brain monoamine systems. Particular attention is being paid to the contributions of these monoamine systems to neuropsychiatric disorders such as Parkinson's disease, depression, schizophrenia, drug abuse, and attention deficit hyperactivity disorder (ADHD). We use rodents as our experimental animals. Mutant mice are used in specific cases.

Several techniques are used in the laboratory:

  1. Electrophysiology-patch clamp
  2. Molecular biology (single cell RT-PCR in combination with patch clamp; gene expression profiling and manipulation)
  3. Electrochemistry (fast cyclic voltammetry at the carbon fiber microelectrode; HPLC)
  4. Immunohistochemistry (double and triple immunolabeling, confocal microscopy)

Funding

Dr. Zhou's research is funded by R01 grants from the National Institute on Drug Abuse and National Institute of Mental Health and grants from private foundations.

Zhou BG Brain

Representative Publications

  • Guo R, Zhou FM, Su CJ, Liu TT, Zhou Y, Fan L, Wang ZH, Liu X, Huang Y, Liu T, Yang J, Chen LH. Epigallocatechin-3-gallate attenuates acute and chronic psoriatic itch in mice: Involvement of antioxidant, anti-inflammatory effects and suppression of ERK and Akt signaling pathways. Biochem Biophys Res Commun. 2018 Feb 19;496(4):1062-1068. doi: 10.1016/j.bbrc.2018.01.122. Epub 2018 Feb 1. PubMed PMID: 29402411.
  • Wang Y, Zhou FM. Striatal But Not Extrastriatal Dopamine Receptors Are Critical to Dopaminergic Motor Stimulation. Front Pharmacol. 2017 Dec 21;8:935. doi: 10.3389/fphar.2017.00935. eCollection 2017. PubMed PMID: 29311936; PubMed Central PMCID: PMC5742616.
  • Hou L, Chen W, Liu X, Qiao D, Zhou FM. Exercise-Induced Neuroprotection of the Nigrostriatal Dopamine System in Parkinson's Disease. Front Aging Neurosci. 2017 Nov 3;9:358. doi: 10.3389/fnagi.2017.00358. eCollection 2017. Review. PubMed PMID: 29163139; PubMed Central PMCID: PMC5675869.
  • Zhou FM, Yang LQ, Zhao RP, Liu D, Li R, Wang Y, Dai ZY, Liu J, Zhang J, Zhou R, Zeng G. [Effect of Sleep in Early Pregnancy on Gestational Diabetes: a Prospective Study.]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2016 Nov;47(6):964-968. Chinese. PubMed PMID: 28598132.
  • Zhao RP, Wang WZ, Cheng GP, Zhang HJ, Zhou FM, Li YY, Wu C, Yang LQ, Zeng G. [Assessment of comprehensive nutritional status and eating behavior among 311 middle aged and aged women with osteoporosis in Chengdu]. Zhonghua Yu Fang Yi Xue Za Zhi. 2017 Jun 6;51(6):551-555. doi: 10.3760/cma.j.issn.0253-9624.2017.06.018. Chinese. PubMed PMID: 28592102.
  • Wei W, Ding S, Zhou FM. Dopaminergic treatment weakens medium spiny neuron collateral inhibition in the parkinsonian striatum. J Neurophysiol. 2017 Mar 1;117(3):987-999. doi: 10.1152/jn.00683.2016. Epub 2016 Dec 7. PubMed PMID: 27927785; PubMed Central PMCID: PMC5340884.

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