James W. Wheless, M.D.

James W. Wheless, M.D.

Professor and Chief
Department of Pediatric Neurology

Chair
Divison of Pediatric Neurology
Le Bonheur Children's Hospital

Director
Le Bonheur Comprehensive Epilepsy Program


Director
Le Bonheur Neuroscience Center

Clinical Director and Chief
Department of Pediatric Neurology
St. Jude Children's Research Hospital

The University of Tennessee Health Science Center
Pediatric Neurology
777 Washington Avenue, Suite 335
Memphis, TN 38105
Phone: (901) 287-5207
Fax: (901) 287-5325
Email: James W. Wheless



Education

  • M.D. Institution: University of Oklahoma, Oklahoma City
  • Residency & Fellowship Training: University of Oklahoma Tulsa Medical College, Tulsa; Child Neurology Fellow, Children's Memorial Hospital, Northwestern University, Chicago; EEG/Epilepsy Fellow, Medical College of Georgia, Augusta

Research Interests

My interests are seizure disorders and epilepsy in children and adolescents. This includes drug therapy, the ketogenic diet, epilepsy surgery, vagus nerve stimulation and magnetoencephalography.

Representative Publications

  • Montouris GD, Wheless JW, Glauser TA. The efficacy and tolerability of pharmacologic treatment options for Lennox-Gastaut syndrome. Epilepsia. 2014 Sep;55 Suppl 4:10-20. doi: 10.1111/epi.12732. PubMed PMID: 25284033.
  • Pellock JM, Wheless JW. Introduction: Recommendations regarding management of patients with Lennox-Gastaut syndrome. Epilepsia. 2014 Sep;55 Suppl 4:1-3. doi: 10.1111/epi.12661. PubMed PMID: 25284031.
  • Wheless JW, Isojarvi J, Lee D, Drummond R, Benbadis SR. Clobazam is efficacious for patients across the spectrum of disease severity of Lennox-Gastaut syndrome: Post hoc analyses of clinical trial results by baseline seizure-frequency quartiles and VNS experience. Epilepsy Behav. 2014 Oct 2;41C:47-52. doi: 10.1016/j.yebeh.2014.09.019. [Epub ahead of print] PubMed PMID: 25282105.
  • Rezaie R, Narayana S, Schiller K, Birg L, Wheless JW, Boop FA, Papanicolaou AC. Assessment of hemispheric dominance for receptive language in pediatric patients under sedation using magnetoencephalography. Front Hum Neurosci. 2014 Aug 21;8:657. doi: 10.3389/fnhum.2014.00657. eCollection 2014. PubMed PMID: 25191260; PubMed Central PMCID: PMC4140211.
  • Papanicolaou AC, Rezaie R, Narayana S, Choudhri AF, Wheless JW, Castillo EM, Baumgartner JE, Boop FA. Is it time to replace the Wada test and put awake craniotomy to sleep? Epilepsia. 2014 May;55(5):629-32. doi: 10.1111/epi.12569. Epub 2014 May 9. PubMed PMID: 24815532.
  • Skalicky AM, Rentz AM, Liu Z, Wheless JW, Pelletier CL, Dunn DW, Frost MD, Nakagawa J, Magestro M, Prestifilippo J, Pashos C. The Burden of Subependymal Giant Cell Astrocytomas Associated With Tuberous Sclerosis Complex: Results of a Patient and Caregiver Survey. J Child Neurol. 2014 Mar 24. [Epub ahead of print] PubMed PMID: 24667738.

View more references (pubmed link)