Connective Tissue Research Group

The Connective Tissue Research Group, a Tennessee Center of Excellence, is a comprehensive center for basic clinical and translational research, education and training and community outreach for the State of Tennessee in diseases affecting the joints, cartilage, skeleton and connective tissues of the body.

The categories of disease the center addresses include classic arthritis associated immune based rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, rheumatic fever), degenerative joint disease including the intervertebral discs, osteoporosis, scleroderma and related fibrosing diseases.

Components groups study etiologic and pathogenetic mechanisms of these diseases using of animal models and in vitro cell culture systems, development of new diagnostic tests and develop new therapies and prosthetics to treat these diseases. The center is also a hub for education and training of pre- and post-doctoral fellows in the arthritides and related diseases and has outreach programs to better educate private physicians in Tennessee and the public about arthritis, bone, joint and connective tissue diseases.

Center for Excellence Diseases of Connective Tissues Logo

Contact Us


Arnold Postlethwaite, Director
Phone: 901-448-4979

Principal Investigators:

David Brand, PhD
Monica L. Brown, DO
Hongbo Chi, PhD
Weikuan Gu, PhD
Karen Hasty, PhD
Andrew H. Kang, MD
Linda K. Myers, MD
Eugene Pinkhassik, PhD
Arnold Postlethwaite, MD
Edward Rosloniec, PhD
Andrzej Slominski, MD, PhD
John Stuart, MD
Ae-Kyeung Yi, PhD