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Electronic Grant Submission

Please contact the Office of Sponsored Programs as soon as you know that you will be submitting a grant application that requires electronic submission so that we can work with you to ensure we meet the submission deadline.

We will provide up-to-date information and training sessions periodically (or upon request) and will post announcements via the research website and campus e-mail.

Cayuse 424

NOTE: All federal grant applications will be submitted using Cayuse 424 rather than the 424 Adobe packages unless the Funding Opportunity Announcement (FOA) requires a different means of submission.

Internal Routing

Internal routing is required prior to submission of ALL grant applications, including those with electronic submission systems that allow the PI to enter data directly into the agency website. In most instances, an institutional official must sign off on the application, either electronically or in paper form, before it is accepted by the agency.

The SP module of the Cayuse 424 system, which replaced PAMS, is used to electronically route all documents that require review and/or signature by the Office of Sponsored Programs. Log in to Cayuse 424 using your net ID and password.


The UTHSC Faculty Senate has approved a 5-working-day internal deadline for all grant applications, including those that must be submitted electronically. The FINAL version of the application is due to be routed in SP on that date. Please note that if an agency has a deadline past 5 p.m. Central time, the UTHSC deadline is 5 p.m. Central. Grant applications that arrive past the 5-working-day advance deadline are not guaranteed to meet the agency submission deadline.

NIH Deadlines


Individual investigators DO NOT need to register with UTHSC is already registered, and the "AOR" is Brenda Murrell. The DUNS# is 94-1884009.

PIs submitting proposals to the NIH need to be registered in NIH Commons to apply for NIH grants. PIs who have been funded, who have applied for NIH grants, or who are NIH reviewers may already be registered. If you do not have an eRA Commons ID or if you need to affiliate an existing ID to UTHSC, please complete the eRA Commons form and forward it to If you are having trouble accessing eRA Commons with a UTHSC-affiliated ID, please send an email to

NIH Multiple PI Leadership

NIH Information on MPI

Helpful links

Feb 6, 2023