Alessandro Iannaccone, M.D., M.S.

Alessandro Iannaccone, M.D., M.S.

Retinal Degeneration & Ophthalmic Genetics Service
Lions Visual Function Diagnostic Lab

Associate Professor
Department of Ophthalmology
The University of Tennessee Health Science Center

The University of Tennessee Health Science Center
Hamilton Eye Institute
930 Madison Ave, Suite 731 (academic)
930 Madison Ave, Suite 400 (clinical)
Memphis, TN 38163 (USA)
Phone: (901) 448-7831 (academic)
(901) 448-6445/6185 (lab)
(901) 448-1241 (UTMG front desk)
Fax: (901) 448-5028 (UT)/1021 (UTMG)
Email: Alessandro Iannaccone


  • M.D. Institution: University La Sapienza, School of Medicine, Rome, Italy
  • M.S. Institution: (Epidemiology) College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, TN
  • Postdoctoral: (Medical Retina Research) Scheie Eye Institute, University of Pennsylvania, Philadelphia; (Pediatric Retinal and Optic Nerve Diseases) University of Tennessee Health Science Center, Memphis
  • Residency: School of Ophthalmology, Institute of Ophthalmology, University of Rome, Italy


Research Interests

Presently, stronger emphasis in my research is on 1) inflammatory and autoimmune aspects of age related macular degeneration and panretinal retinopathies; 2) hereditary retinal diseases such as X-linked and dominant retinitis pigmentosa (RP), Leber's congenital amaurosis, Usher syndrome (RP with hearing loss) and Bardet-Biedl syndrome (RP with obesity, polydactyly, and other systemic manifestations); and 3) nutritional influences on macular function and macular pigment.

Recent Publications

  • Chou CM, Nelson C, Tarlé SA, Pribila JT, Bardakjian T, Woods S, Schneider A, Glaser T. Biochemical Basis for Dominant Inheritance, Variable Penetrance, and Maternal Effects in RBP4 Congenital Eye Disease. Cell. 2015 Apr 23;161(3):634-646. doi: 10.1016/j.cell.2015.03.006. PubMed PMID: 25910211.
  • Zhong M, Sun H. A Genetic Clog in the Vitamin A Transport Machinery. Cell. 2015 Apr 23;161(3):435-437. doi: 10.1016/j.cell.2015.04.020. PubMed PMID: 25910203.
  • Mathis A, Stemmler MB, Herz AV. Probable nature of higher-dimensional symmetries underlying mammalian grid-cell activity patterns. Elife. 2015 Apr 24;4. doi: 10.7554/eLife.05979. [Epub ahead of print] PubMed PMID: 25910055.
  • Yang MK, Wee WR, Kwon JW, Han YK. Anterior Chamber Depth and Refractive Change in Late Postoperative Capsular Bag Distension Syndrome: A Retrospective Analysis. PLoS One. 2015 Apr 24;10(4):e0125895. doi: 10.1371/journal.pone.0125895. eCollection 2015. PubMed PMID: 25910003.
  • Luo X, Cideciyan AV, Iannaccone A, Roman AJ, Ditta LC, Jennings BJ, Yatsenko SA, Sheplock R, Sumaroka A, Swider M, Schwartz SB, Wissinger B, Kohl S, Jacobson SG. Blue Cone Monochromacy: Visual Function and Efficacy Outcome Measures for Clinical Trials. PLoS One. 2015 Apr 24;10(4):e0125700. doi: 10.1371/journal.pone.0125700. eCollection 2015. PubMed PMID: 25909963.
  • Li LJ, Aris I, Su LL, Tint MT, Cheung CY, Ikram MK, Gluckman P, Godfrey KM, Tan KH, Yeo G, Yap F, Kwek K, Saw SM, Chong YS, Wong TY, Lee YS. Associations of Maternal Retinal Vasculature with Subsequent Fetal Growth and Birth Size. PLoS One. 2015 Apr 24;10(4):e0118250. doi: 10.1371/journal.pone.0118250. eCollection 2015. PubMed PMID: 25909909.

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