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Pharmacology Faculty Research Interests

Suleiman Bahouth, PhD
Associate Professor - Department of Pharmacology

sbahouth@uthsc.edu

Research Interests: Identification of motifs in the human beta-1-adrenergic receptor that are involved in its coupling to G proteins, internalization, recycling, and resensitization after agonist exposure.

Sharyn D. Baker, PharmD, PhD
Associate Member - Department of Pharmaceutical Sciences, St. Jude

Sharyn.baker@stjude.org

Research Interests: Clinical Pharmacology of tyrosine kinase inhibitors; Tyrosine kinase inhibitors for the treatment of childhood acute myelogenous leukemia; Pharmacokinetic variability of anticancer agents.

Taosheng Chen, PhD
Assistant Member - Department of Chemical Biology and Therapeutics, St. Jude

taoscheng.chen@stjude.org

Research Interests: Regulation of PXR and drug metabolism; regulation of PAX3-FKHR in alveolar rhabdomyosarcoma.

George Cook, PhD
Professor - Department of Pharmacology

gcook@uthsc.edu

Research Interests: Control of genes regulating fat metabolism, concentrating on the control of fatty acid oxidation in liver and heart in diabetes, during fasting and in the normal, fed state.

Alex Dopico, MD, PhD
Assistant Professor and Chair, Department of Pharmacology

adopico@uthsc.edu

Research Interests: Voltage-gated ion channels in excitable cells as relevant targets of small amphiphilic drugs and membrane lipids.

Marshall Elam, MD, PhD
Associate Professor - Department of Pharmacology

melam@uthsc.edu

Research Interests: Regulation of hepatic lipid/lipoprotein synthesis and secretion by insulin in obesity and type II diabetes; Regulation of Sterol-Regulatory-Element Binding Protein-1c (SREBP-1c) transcription by insulin, cyclic-AMP, and polyunsaturated fatty acids.

Kafait Malik, PhD, DSc
Professor - Department of Pharmacology

kmalik@uthsc.edu

Research Interests: Cellular and molecular mechanisms of neurohumoral interactions involved in vascular smooth muscle cell hyperplasia and hypertrophy and hypertension.

Edwards Park, PhD
Associate Professor - Department of Pharmacology

epark@uthsc.edu

Research Interests: Mechanisms by which hormones regulate gene expression in diabetes, hyperthyroidism and obesity.

Rajendra Raghow, PhD
Professor - Department of Pharmacology

rraghow@uthsc.edu

Research Interests: Mechanisms of transcriptional and post-transcriptional regulation of homeobox genes Msx1/3.

Kazuko Sakata, PhD
Assistant Professor - Department of Pharmacology

ksakata@uthsc.edu

Research Interests: Current projects focus on studying the roles of activity-dependent expression of BONF (Brain Derived Neurotrophic Factor) in depression and anxiety, using molecular and biochemical, electrophysiologyical, and behavioral techniques with genetically modified mice.

Burt Sharp, MD
Professor and Chair - Department of Pharmacology

bsharp@uthsc.edu

Research Interests: Nicotine self-administration-induced plasticity in stress-reponsive brain systems: involvement of genes, neurotransmitters, and hormones.

Alex Sparreboom, PhD
Associate Member - Department of Pharmaceutical Sciences, St. Jude

alex.sparreboom@stjude.org

Research Interests: Role of solute carriers in renal and hepatic anticancer drug clearance; Genetic factors contributing to interindividual variability in anticancer drug disposition.

Jeffery Steketee, PhD
Associate Professor - Department of Pharmacology

jsteketee@uthsc.edu

Research Interests: Neural mechanisms of drug addiction.

Clinton Stewart, PharmD
Associate Member - Department of Pharmaceutical Sciences

clinton.stewart@stjude.org

Research Interests: Use of preclinical models that study the pharmacokinetics and pharmacodnamics of novel anticancer drugs to enhance the design of clinical trials in children with cancer.

Parker Suttle, PhD
Associate Professor - Department of Pharmacology

psuttle@uthsc.edu

Research Interests: Regulation of mammalian DNA topoisomerase IIa gene expression and the role of topo IIa in G2/M cell cycle arrest.

Wen Lin Sun, PhD
Assistant Professor - Department of Pharmacology

wsun5@uthsc.edu

Research Interests: Neurobiological mechanisms underlying drug addiction.

Trevor Sweatman, PhD
Associate Professor - Department of Pharmacology

tsweatman@uthsc.edu

Research Interests: Preclinical development of novel antitumor agents

Steven Tavalin, PhD
Assistant Professor - Department of Pharmacology

stavalin@uthsc.edu

Research Interests: Regulation of synaptic transmission and neuronal excitability by localized signaling systems.

Fu-Ming Zhou, PhD
Assistant Professor - Department of Pharmacology

fzhou3@uthsc.edu

Research Interests: Dopamine and serotonin systems in the brain and their involvement in neuropsychiatric disorders.

May 26, 2022