Division Publications


  • Eison TM, Ault BH, Jones DP, Chesney RW, Wyatt RJ: Post-streptococcal acute glomerulonephritis in children: clinical features and pathogenesis. Pediatric Nephrology 26: 165-180
  • Gharavi AG, Kiryluk K, Choi M, Li Y, Hou P, Xie J, Sanna-Cherchi S, Men CJ, Julian BA, Wyatt RJ, Novak J, He JC, Wang H, Lv J, Zhu L, Wang W, Wang Z, Yasuno K, Gunel M, Mane S, Umlauf S, Tikhonova I, Beerman I, Savoldi S, Magistroni R, Ghiggeri GM, Bodria M, Lugani F, Ravani P, Ponticelli C, Allegri L, Boscutti G, Frasca G, Amore A, Peruzzi L, Coppo R, Izzi C, Viola BF, Prati E, Salvadori M, Mignani R, Gesualdo L, Bertinetto F, Mesiano P, Amoroso A, Scolari F, Chen N, Zhang H, Lifton RP: Genome-wide association study identifies susceptibilty loci for IgA nephropathy. Nature Genetics 43: 321-327
  • Howard SC, Jones DP, Pui C-H: The tumor lysis syndrome. New England Journal of Medicine 364: 1844-1854
  • Hickey CA, Beattie TJ, Cowieson J, Miyashita Y, Strife CF, Frem JC, Peterson JM, Butani L, Jones DP, Havens PL, Patel HP, Wong CS, Andreoli SP, Rothbaum RJ, Beck AM, Tarr PI: Early volume expansion during diarrhea and relative nephroprotection during subsequent hemolytic uremic syndrome. Archives of Adolescent and Pediatric Medicine 164: 884-889
  • Kiryluk K, Moldoveanu Z, Sanders JT, Eison TM, Suzuki H, Julian BA, Novak J, Gharavi AG, Wyatt RJ: Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schönlein purpura nephritis. Kidney International 80: 79-87
  • Novak J, Moldoveanu Z, Julian BA, Julian BA, Raska M, Wyatt RJ, Suzuki Y, Tomino Y, Gharavi AG, Mestecky J, Suzuki H: Aberrant glycosylation of IgA1 and anti-glycan antibodies in IgA nephropathy: role of mucosal immune system. Advances in Otorhinology 72: 60-63, 2011
  • Novak J, Raskova-Kafkova L, Suzuki H, Tomana M, Matousovic K, Brown R, Hall S, Sanders JT, Eison, TM, Moldoveanu Z, Novak L, Novak Z, Mayne R, Julian BA, Mesctecky J, Wyatt RJ: IgA1 immune complexes from pediatric patients with IgA nephropathy activatecultured human mesangial cells. Nephrology, Dialysis and Transplantation 26: 3451-3457
  • Papeta N, Kiryluk K, Patel A, Sterken R, Kacak N, Snyder HJ, Mhatre AN, Julian BA, Wyatt RJ, Novak J, Wyatt CM, Ross MJ, Winston JA, Klotman ME, Cohen DJ, Appel GB, D’Agati VD, Klotman PE, Gharavi AG: APOL1 genetic variants are associated with susceptibility to focal segmental glomerulosclerosis and HIV-1 associated nephropathy but not IgA nephropathy in African Americans. Journal of the American Society of Nephrology 22: 1991-1996
  • Suzuki H, Kiryluk K, Novak J, Moldoveanu Z, Herr HB, Renfrow M, Wyatt RJ, Scolari F, Mestecky J, Gharavi AG, Julian BA. The pathophysiology of IgA nephropathy. Journal of the American Society of Nephrology 22: 1795-1803
  • Lavigne K, Woodford SY, Barker C, Julian BA, Novak J, Moldoveanu Z, Gharavi AG, Wyatt RJ: Familial IgA nephropathy in southeastern Kentucky. Clinical Nephrology 73: 115-121
  • Lau KK, Suzuki H, Novak J, Wyatt RJ: Pathogenesis of Henoch-Schoenlein purpura nephritis. Pediatric Nephrology 25: 19-26
  • Hastings MC, Eison TM, Wyatt RJ: Invited commentary: Prevention and treatment of kidney disease in Henoch-Schoenlein purpura. Evidence-Based Child Health: A Cochrane Review Journal 5: 703-708, 2010
  • Richey PA, Disessa TG, Somes GW, Alpert BS, Jones DP: Left ventricular geometry in children and adolescents with primary hypertension. American Journal of Hypertension 23: 24-29
  • Rajasekaran S, Jones DP, Avent Y, Shaffer ML, Elbahlawan L, Henderson N, Barfield RC, Morrison RR, Tamburro RF: Outcomes of hematopoietic stem cell transplant patients who received continuous renal replacement therapy in a pediatric oncology intensive care unit. Pediatric Critical Care Medicine 11: 699-706
  • Elbahlawan L, West NK, Avent Y, Cheng C, Liu W, Barfield RC, Jones DP, Rajasekaran S, Morrison RR: Impact of continuous renal replacement therapy on oxygenation in children with acute lung injury after allogeneic hematopoietic stem cell transplantation. Pediatric Blood and Cancer 55: 540-555
  • Sanders JT, Jones DP: Workup of the child with hypertension. Lebanese Medical Journal 58: 156-160
  • Kiryluk K, Julian BA, Wyatt RJ, Scolari F, Zhang H, Novak J, Gharavi AG: Genetic studies of IgA nephropathy: past, present, and future. Pediatric Nephrology 25: 2257-2268
  • Hastings MC, Moldoveanu Z, Julian BA, Novak J, Sanders JT, McGlothan KR, Gharavi AG, Wyatt RJ: Galactose-deficient IgA1 in african americans with IgA nephropathy: serum levels and heritability. Clinical Journal of the American Society of Nephrology 5: 2069-2074
  • Daw NC, Gregornik D, Rodman J, Marina N, Wu J, Kun LE, Jenkins JJ, McPherson V, Wilimas J, Jones DP: Renal function after ifosphamide, carboplatinum and etoposide (ICE) chemotherapy, nephrectomy and radiotherapy in children with Wilm's tumor. European Journal of Cancer 45: 99-106
  • Delos Santos NM, Ault BH: "Hematuria" in Pediatric Nephrology for Primary Care A.J. Barakat and R.W. Chesney, eds, American Academy of Pediatrics, pp 143-158
  • Hastings MC, Wyatt RJ: “Glomerular Diseases” in Pediatric Nephrology for Primary Care, A.J. Barakat and R.W. Chesney, eds, American Academy of Pediatrics, pp 173-192
  • Chesney RW: “Tubular Disorders ” in Pediatric Nephrology for Primary Care, A.J. Barakat and R.W. Chesney, eds, American Academy of Pediatrics, pp 193-211
  • Jones DP: “Hypertension” in Pediatric Nephrology for Primary Care, A.J. Barakat and R.W. Chesney, eds, American Academy of Pediatrics, pp 287-311
  • Lau KK, Yang Y, Cook GA, Wyatt RJ, Nishimura H: Control of aquaporin 2 expression in collecting ducts of quail kidneys. General and Comparative Endocrinology 160: 288-294
  • Nezakatagoo N, Sanders JT, Jones DP: Brachial artery-to-brachial arterio-venous fistula in a pediatric patient. Nephrology Reviews 1:E3
  • Li R, Richey PA, DiSessa TG, Alpert BS, Jones DP: Blood aldosterone-to-renin ratio, ambulatory blood pressure, and left ventricular mass in children. Journal of Pediatrics 155: 170-175
  • Jones DP, Richey PA, Alpert BS: Comparison of ambulatory blood pressure reference standards in children evaluated for hypertension. Blood Pressure Monitoring 14: 103-107
  • Suzuki H, Fan R, Zhang Z, Brown R, Hall S, Julian BA, Chatham WW, Suzuki Y, Wyatt RJ, Moldoveanu Z, Lee JY, Robinson J, Tomana M, Tomino Y, Mestecky J, Jan Novak J: Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity. Journal of Clinical Investigation 119: 1450-145
  • Mestecky J, Tomana M, Moldoveanu Z, Julian BA, Suzuki H, Matousovic K, Renfrow MB, Novak L, Wyatt RJ, Novak J: Role of aberrant glycosylation of IgA1 molecules in the pathogenesis of IgA nephropathy. Kidney and Blood Pressure Research 31:29-37
  • Chesney RW: The role of the kidney in protecting the brain against cerebral edema and neuronal cell swelling. Journal of Pediatrics 152:4-6
  • Greenfield SP, Chesney RW, Carpenter M, Moxey-Mins M, Nyberg L, Hoberman A, Keren R, Matthews R, Mattoo T: Vesicoureteral reflux: the RIVUR study and the way forward. Journal of Urology 179:405-407
  • Richey PA, DiSessa TG, Hastings MC, Somes GW, Alpert BS, Jones DP: Ambulatory blood pressure and increased left ventricular mass in children at risk for hypertension. Journal of Pediatrics 152:343-348
  • Suzuki H, Moldoveanu Z, Hall S, Brown R, Vu HL, Novak L, Julian BA, Tomana M, Wyatt RJ, Edberg JC, Alarcon GS, Kimberly RP, Tomino Y, Mestecky J, Novak J: IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1. The Journal of Clinical Investigation 118:629-639
  • Spencer JD, Hastings MC, Rye AK, English K, Ault BH: Gastroenteritis caused by Edwardsiella tarda in a pediatric renal transplant recipient. Pediatric Transplantation 152: 343-348
  • Sanders JT, Wyatt RJ: IgA nephropathy and Henoch-Schoenlein purpura nephritis. Current Opinion in Pediatrics 20: 163-170
  • McDonald RA, Smith JM, Ho M, Lindblad R, Ikle D, Grimm P, Wyatt R, Azar M, Liereman D, Bridges N, Harmon W; CCTPT Study Group: Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroids. American Journal of Transplantation 8: 984-989
  • Gharavi AG, Moldoveanu Z, Wyatt RJ, Barker CV, Woodford SY, Lifton RJ, Mestecky J, Novak J, Julian BA: Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy. Journal of the American Society of Nephrology 19: 1008-1014
  • Davidoff AM, Giel DW, Jones DP, Jenkins JJ, Krasin MJ, Hoffer FA, Williams MA, Dome JS: The feasibility and outcome of nephron-sparing surgery for children with bilateral Wilms tumor. The St. Jude Children's Research Hospital experience: 1999-2006. Cancer 112: 2060-2070
  • Jones DP, Richey PA, Alpert BS, Li R: Serum uric acid and ambulatory blood pressure in children with primary hypertension. Pediatric Research 64: 556-561
  • Zepeda-Orozco D, Ault BH. Jones DP: Factors associated with acute renal failure in children with rhabdomyolysis. Pediatric Nephrology 23: 2281-2284
  • Brown ML, Chesney PJ, Ault BH, Delos Santos NM, Truong LD, Lohr KM, Myers LK: Fever and rash. Cinical Pediatrics (Philadelphia) 47: 610-614
  • Jones DP, Spunt SL, Green D, Springate JE: Renal late effects in patients treated for cancer in childhood: A report from the Children’s Oncology Group. Pediatric Blood and Cancer 51: 724-731
  • Williams MA, Giel DW, Hastings MC: Endoscopic Deflux injection for pediatric transplant reflux: A feasible alternative to open ureteral reimplant. Journal of Pediatric Urology 4: 341-344
  • Lau KK, Ault BH, Jones DP, Butani L: Induction therapy for pediatric focal proliferative lupus nephritis: cyclophosphamide vs. mycophenolate mofetil. Journal of Pediatric Health Care 22: 282-288
  • Jones DP, Richey PA, Alpert BS: Validation of the AM5600 ambulatory blood pressure monitor in children and adolescents. Blood Pressure Monitoring 13: 349-351
  • Hastings MC, Delos Santos NM, Wyatt RJ: Renal survival in pediatric patients with IgA nephropathy (letter). Pediatric Nephrology 22:317-318
  • Chesney RW, Jones DP: Is there a role for beta-adrenergic blockers in treating hypertension in children? (editorial) Journal of Pediatrics 150: 121-122
  • Lau K, Jones D, Ault B: Prognosis of lupus membranous nephropathy (letter). Lupus 16: 70
  • Lau K, Jones D, Gaber O, Nezakatgoo N: Use of a “composite” vascular access graft in a young child on hemodialysis. Hemodialysis International 11: 190-192
  • Julian BA, Wyatt RJ, Matousovic K, Moldoveanu Z, Mestecky J, Novak J: IgA Nephropathy: A Clinical Overview, in Tomino Y, ed, IgA Nephropathy Today, Contrib Nephrol. Basel, Karger, 2007, vol 157, pp 19-26
  • Suzuki H, Moldoveanu Z, Hall S, Brown R, Julian BA, Wyatt RJ, Tomana M, Tomino Y, Novak J, Mestecky J: IgA nephropathy: Characterization of IgG antibodies specific for galactose-deficient IgA, in Tomino Y, ed, IgA Nephropathy Today, Contributions to Nephrology, Basel, Karger, 2007, vol 157, pp 129-133
  • Novak J, Moldoveanu Z, Renfrow MB, Yanagihara T, Suzuki H, Raska M, Hall S, Brown R, Huang W-Q, Goepfert A, Kilian M, Poulsen K, Tomana M, Wyatt RJ, Julian BA, Mestecky J: IgA nephropathy and Henoch-Schoenlein purpura nephritis: Aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells, in Tomino Y, ed, IgA Nephropathy Today, Contributions to Nephrology, Basel, Karger, 2007, vol 157, pp 134-138
  • Hastings MC, Wyatt RJ, Ault BH, Jones DP, Lau KK, Gaber AO, Gaber LW: Diagnosis of de novo localized thrombotic microangiopathy by surveillance biopsy. Pediatric Nephrology 22: 742-746
  • Raska M, Moldoveanu Z, Suzuki H, Brown R, Kulhavy R, Andrasi J, Hall S, Vu HL, Carlsson F, Lindahl G, Tomana M, Julian BA, Wyatt RJ, Mestecky J, Novak J: Identification and characterization of CMP-NeuAc:GalNac-IgA1 a2, 6-sialytransferase in IgA1-producing cells. Journal of Molecular Biology 369: 69-78
  • Moldoveanu Z, Wyatt RJ, Lee J, Tomana M, Julian BA, Mestecky J, Huang W-Q, Anreddy SR, Hall S, Hastings MC, Lau KK, Cook WJ, Novak J: Elevated serum levels of galactose-deficient IgA in patients with IgA nephropathy. Kidney International 71: 1148-1154
  • Beerman I, Novak J, Wyatt RJ, Julian BA, Gharavi AG: The genetics of IgA nephropathy. Nature Nephrology Clinical Practice 3: 325-338
  • Inaba H, Jones DP, Gaber LW, Shenep JL, Call SK, Pui C-H, Razzouk BI: BK virus-induced tubulointerstitial nephritis in a child with acute lymphoblastic leukemia. Journal of Pediatrics 151: 215-217
  • Bashir H, Crom D, Metzger M, Mulcahey J, Jones D, Hudson MM: Cisplatin-induced hypomagnesemia and cardiac dysrhythmia. Pediatric Blood and Cancer 49: 867-869
  • Giel DW, Williams MA, Jones DP, Davidoff AM, Dome JS: Renal function outcomes in patients treated with nephron sparing surgery for bilateral Wilm's tumor. Journal of Urology 178: 1786-1789
  • Sheth P, Delos Santos NM, Seth A, LaRusso NF, Rao RK: Lipopolysaccharide disrupts tight junctions in cholangiocyte monolayers by a c-Src, TLR4 and LBP-dependent mechanism. American Journal of Physiology Gastrointestinal Liver Physiology 293: G308-G318
  • Julian BA, Wittke S, Haubitz M, Zurbig P, Schiffer E, McGuire BM, Wyatt RJ, Novak J: Urinary biomarkers in IgA nephropathy and other IgA-related diseases. World Journal of Urology 25: 467-476
  • Nishimura H, Yang Y, Lau K, Kuykindoll RJ, Fan Z, Yamaguchi K, Yamamoto T: Aquaporin-2 water channel in developing quail kidney: possible role in programming adult homeostasis. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 293: R2147-R2158
  • Lau KK, Wyatt RJ, Moldoveanu Z, Tomana M, Julian BA, Hogg RJ, Lee JY, Huang WQ, Mestecky J, Novak J: Serum levels of glactose-deficient IgA in children with IgA nephropathy and Henoch-Shoenlein purpura. Pediatric Nephrology 22: 2067-2072
  • Julian BA, Wittke S, Novak J, Coon JJ, Zurbig P, Schiffer E, Haubitz M, Moldoveanu Z, Calcatera SM, Wyatt RJ, Sykora J, Sladkova E, Hes O, Mischak H, McGuire BM: Electrophoretic methods for analysis of urinary polypeptides in IgA-associated renal disease. Electrophoresis 28:4469-4483
  • Delos Santos NM, Gardner LA, White SW, Bahouth SW: Characterization of the residues in helix 8 of the beta-1 adrenergic receptor that are involved in coupling the receptor to G proteins. Journal of Biological Chemistry 281: 12896-12907
  • Chesney RW, Brewer E, Moxey-Mims M, Watkins S, Furth SL, Harmon WE, Fine RN, Portman RJ, Warady BA, Salusky IB, Langman CB, Gipson D , Scheidt P, Feldman H, Kaskel FJ, Siegel NJ: Report of an NIH task force on research priorities in chronic kidney disease in children. Pediatric Nephrology 21: 14-25
  • Lau KK, Ault BH: Teaching case: A child with recurrent episodes of dark urine: question. Pediatric Nephrology 21: 271
  • Lau KK, Ault BH: Teaching case: A child with recurrent episodes of dark urine: answer. Pediatric Nephrology 21: 272-274
  • Lau KK, Jones DP, Hastings MC, Gaber LW, Ault BH: Short term outcomes of severe lupus nephritis in a cohort of predominately African-American children. Pediatric Nephrology 21: 655-662
  • Lau KK, Delos Santos NM: Pediatric C1q nephropathy and incidental proteinuria (letter). Pediatric Nephrology, 21: 883
  • Hogg RJ, Lee J, Nardelli N, Julian BA, Cattran D, Waldo B, Wyatt R, Jennette C, Sibley R, Hyland K, Fitzgibbons L, Hirschman G, Donadio J, Holub BJ: Placebo controlled clinical trial evaluating omega-3 fatty acids and alternate day prednisone in patients with IgA nephropathy. Clinical Journal of the American Society of Nephrology 1: 467-474
  • McGlothan KR, Wyatt RJ, Ault BH, Hastings MC, Rogers T, DiSessa T, Jones DP: Predominance of nocturnal hypertension in pediatric renal allograft recipients. Pediatric Transplantation 10: 558-564
  • Han X, Patters AB, Jones DP, Zelicovic I, Chesney RW: The taurine transporter: mechanisms of regulation. Acta Physiology (Oxford) 187: 61-73
  • Lau KK, Delos Santos NM, Hastings MC, Ault BH, Jones DP, Roy III S, Ault BH, Wyatt RJ: Tularemia infection in a pediatric patient with chronic renal insufficiency and inguinal lymphadenopathy. Infectious Diseases in Clinical Practice 14: 248-250
  • Broides A, Ault BH, Arthus MF, Bichet DG, Conley ME: Severe combined immunodeficiency associated with nephrogenic diabetes insipidis and a deletion in the Xq28 region. Clin Immunol 120: 147-155
  • Zeitoun O, Delos Santos NM, Gardner LA, White SW, Bahouth SW: Mutagenesis within helix 6 of the human beta1-adrenergic receptor identifies lysine324 as a residue involved in imparting the high-affinity binding state of agonists. Molecular Immunology 70: 838-850
  • Hastings MC, Wyatt RJ, Jones DP, Lau KK, Powell SL, Hayes DW, Gaber LW, Gaber AO, Ault BH: Five years' experience with Thymoglobulin induction in a pediatric renal transplant population. Pediatric Transplantation 10: 805-810
  • Schachter AD, Benfield MR, Wyatt RJ, Grimm PC, Fennell RS, Herrin JT, Lirenman DS, McDonald RA, Munoz-Arizpe R, Harmon WE: Sirolimus pharmacokinetics in pediatric renal transplant recipients receiving calcineurin inhibitor co-therapy. Pediatric Transplantation 10: 914-919
  • Lau KK, Hastings MC, Arnold SL, Jones DP, Boulden T, Shokouh-Amiri H, Wyatt RJ, Ault BH: Bartonella infection presenting With prolonged fever in a pediatric renal transplant recipient. The Internet Journal of Infectious Diseases 5: 1
  • Hogg R, Fitzgibbons L, Bunke M, Ault B, Baqi N, Trachtman H, Swinford R: Mycophenolate mofetil in children with frequently relapsing nephrotic syndrome. Clinical Journal of the American Society of Nephrology 1: 1173-1178
  • Wyatt RJ, Novak J, Gaber LW, Lau KK: Immunoglobulin A nephropathy and Henoch-Schonlein purpura, in Clinical Pediatric Nephrology, 2nd edition, Kerr KK, Schnapper HW, Makker SP, eds, Informa UKL Ltd , pp 213-222
  • Han X, Chesney RW: Is TauT an anti-apoptotic gene? Advances in Experimental Medicine and Biology 583: 59-67
  • Han X, Chesney RW: Mechanisms of regulation of taurine transporter activity: a complex interplay of regulatory systems. Advances in Experimental Medicine and Biology 583: 79-90