Dr. Mary Kathleen Mazel
Assistant Professor of Pediatrics
Dr. Mazel received her medical degree from the University of Southern California, Los Angeles, California in 2004. She completed her pediatric residency at USC + LAC Medical Center, Los Angeles, California in 2007 and was a pediatric critical care fellow at the Mattel Children’s Hospital, UCLA Medical Center in Los Angeles, California from 2008-2011. Dr. Mazel joined the Pediatric Critical Faculty at Le Bonheur Children’s Hospital at UTHSC in July, 2011.
Dr. Mazel’s research interests include developing rapid diagnostic tests to detect bloodstream infections. The aims of her research include the following : 1) To develop a DNA assay for the rapid detection of bacterial and fungal bloodstream infections in pediatric patients. 2) To compare the results obtained from the DNA assays to blood cultures in order to determine if the DNA assay identifies the bacteria and fungal bloodstream infections faster and maintains the accuracy of the standard blood culture. 3) To develop a DNA assay for the rapid detection of antibiotic resistant bacteria and antimycotic resistant fungus in pediatric patients that have bloodstream infections. The development of rapid diagnostic methods to detect bloodstream infections faster has been recognized in the medical community as a way to drastically improve the medical care given to patients by supplementing conventional blood culture results.
Dr. Mazel’s community work includes: 1) Mentoring high risk children and adolescents, 2) Starting and managing the USC Student Run Free Clinic that provided continuity of care for homeless men, women, and children. 3) Lobbying for health care reform at the state and national capitols.
- Guerreiro, H., Croda, J,. Flannery, B., Mazel, M., Galvao,R., Levett, P., Ko, A. 2001. Leptospiral proteins recognized during the humeral immune response to leptosirosis in humans. Infection and Immunity. 69 (8): 4958-68.
- Haake, D., Chao, G., Zuerner, R., Barnett, J. Mazel, M., Matsunaga, J., Levett, P., Bolin, C. 2000. The Leptospiral Major Outer Membrane Protein LipL32 is a Lipoprotein Expressed during Mammalian Infection. Infection and Immunity. 68 (4): 2276-85.
- Haake, D., Martinich, C., Summers, T., Shang, E,, Pruetz, J., McCoy, A., Mazel, M., Bolin, A, 1998. Charateriztion of Leptospiral Outer Membrane Lipoprotein LipL36: Downregulation Associated with Late-Log-Phase Growth and Mammalian Infection. Infection and Immunity. 66 (4): 1579-1587.
- Haake, D., Mazel, M., McCoy, A., Milward, F., Chao, G., Matsunaga, J., Wagar, E. 1999. Leptospiral Outer Membrane Proteins OmpL1 and LipL 41 Exhibit Synergistic Immunoprotection. Infection and Immunity. 67 (12): 6572-6582.
Department of Pediatrics
Critical Care Division
LeBonheur Children's Hospital
Children’s Foundation Research Center
50 N Dunlap, 3rd Floor
Memphis, TN 38103