FOR IMMEDIATE RELEASE.
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Anne W. Manning
UTHSC CANCER RESEARCHER TIGYI NAMED VAN VLEET CHAIR
Memphis, Tennessee (April 24, 2006) – Gabor J. Tigyi, MD, PhD, professor of physiology at the University of Tennessee Health Science Center (UTHSC), has been named the Harriet S. Van Vleet Professor in Oncology Research.
R. Caudle, MD, interim executive dean of the UTHSC College of Medicine noted
that, “Dr. Tigyi's groundbreaking research in lipid mediators has
established the UT Health Science Center as a global leader in this field.
His continuing work has changed and broadened our ways of thinking about
cell growth regulation and has profound implications for the future
direction of cancer research. Furthermore, Dr.Tigyi has been a primary leader
in launching UT's state-wide cancer institute initiative. This chair
acknowledges Dr. Tigyi's academic success. He has clearly earned this
P. Wall, MD, interim dean of the UTHSC College of Medicine,
Dr. Tigyi’s 1986 discovery of lipid molecules that regulate cell growth launched an entirely new field of research that today is populated by fellow investigators around the world. As Dr. Tigyi explained, “I built my career on something unexpected. I was going down one path which proved to be wrong and quite by chance discovered a new type of lipid mediators in the process.” Dr. Tigyi’s initial work was in isolating growth regulatory lipids and identifying their structure.
As history and science have since proven, growth regulatory lipid mediators are important to a whole host of biological responses, including cell survival, degenerative diseases, cancer invasion and metastasis. They also play a major role in organ transplant rejection and are critical to the development of gyri (folds in the brain). Major pharmaceutical companies such as Novartis and Merck have succeeded in producing mimics of these lipid mediators that treat multiple sclerosis and regulate immunity, which leads to organ rejection.
Dr. Tigyi is
currently working on three National Institutes of Health (NIH) grants to
explore different applications of lipids to cancer research. Collaborators on
his various projects include Abby Parrill, PhD, professor of chemistry at the
his role as associate director for basic sciences at the UT Cancer Institute
(UTCI), Dr. Tigyi is currently part of a task force that is drafting an
entirely new model for cancer care for the state of
internationally and widely published, Dr. Tigyi enjoys an ongoing Visiting Professorship
This study quantifies the economic impact of the UTHSC on the economy of the state of Tennessee for FY2010.
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