Catherine Kaczorowski, Ph.D.

Catherine Kaczorowski, Ph.D.

Assistant Professor
Department of Anatomy and Neurobiology

The University of Tennessee Health Science Center
855 Monroe Avenue, Suite 515
Memphis, TN 38163
Tel: (901) 448-2178
Fax: (901) 448-7193
Labs: 228 Wittenborg Anatomy Building
Office: 231 A Wittenborg Anatomy Building
Email: Catherine Kaczorowski

Spotlight Interview

American Federation for Aging Research


  • Ph.D. Institution: Northwestern University, Neuroscience
  • Postdoctoral: Medical College of Wisconsin and University of Wisconsin-Milwaukee, Physiology and Bioengineering & Biotechnology


To identify early causative events that underlie cognitive deficits associated with 'normal' aging and Alzheimer's disease. Using multidisciplinary approaches that combine innovative high resolution and high throughput membrane proteomics, transcriptomics, viral-based gene transduction approaches, behavioral assays, and electrophysiology, our research aims to understand how misregulated membrane proteins in the hippocampus of aging and AD mouse models alter hippocampal neuron excitability and memory. Our goal is to transform basic discoveries into treatments that prevent and cure dementias in aging.

Representative Publications

  • Garfinkel BP, Arad S, Neuner SM, Netser S, Wagner S, Kaczorowski CC, Rosen CJ, Gal M, Soreq H, Orly J. HP1BP3 expression determines maternal behavior and offspring survival. Genes Brain Behav. 2016 Sep;15(7):678-88. doi: 10.1111/gbb.12312. PubMed PMID: 27470444.
  • Neuner SM, Garfinkel BP, Wilmott LA, Ignatowska-Jankowska BM, Citri A, Orly J, Lu L, Overall RW, Mulligan MK, Kempermann G, Williams RW, O'Connell KM, Kaczorowski CC. Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging. Neurobiol Aging. 2016 Oct;46:58-67. doi: 10.1016/j.neurobiolaging.2016.06.008. PubMed PMID: 27460150; PubMed Central PMCID: PMC5018442.
  • Neuner SM, Wilmott LA, Hoffmann BR, Mozhui K, Kaczorowski CC. Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. Behav Brain Res. 2016 Jun 2. pii: S0166-4328(16)30356-4. doi: 10.1016/j.bbr.2016.06.002. PubMed PMID: 27265785.
  • Graves AR, Moore SJ, Spruston N, Tryba AK, Kaczorowski CC. Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons. J Neurophysiol. 2016 Aug 1;116(2):466-71. doi: 10.1152/jn.00186.2016. PubMed PMID: 27146982; PubMed Central PMCID: PMC4978785.
  • Prisco AR, Hoffmann BR, Kaczorowski CC, McDermott-Roe C, Stodola TJ, Exner EC, Greene AS. Tumor Necrosis Factor α Regulates Endothelial Progenitor Cell Migration via CADM1 and NF-kB. Stem Cells. 2016 Jul;34(7):1922-33. doi: 10.1002/stem.2339. PubMed PMID: 26867147; PubMed Central PMCID: PMC4931961.
  • Clayton T, Poe MM, Rallapalli S, Biawat P, Savić MM, Rowlett JK, Gallos G, Emala CW, Kaczorowski CC, Stafford DC, Arnold LA, Cook JM. A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model. Int J Med Chem. 2015;2015:430248. doi: 10.1155/2015/430248. Review. PubMed PMID: 26682068; PubMed Central PMCID: PMC4657098.

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