Bob M. Moore II, Ph.D.

Bob M. Moore II, Ph.D.

Professor


Department of Pharmaceutical Sciences


The University of Tennessee Health Science Center
874 Union Avenue, Room 327D
Memphis, TN 38163
Tel: (901) 448-6085
Fax: (508) 448-6828
Email: Bob M. Moore



Education

  • B.S. in Chemistry, Indiana State University, 1983
  • M.S. in Chemistry, Indiana State University, 1989
  • Ph.D. (Medicinal Chemistry), University of Kansas, 1995

Research Interests

Research in Dr. Moore's lab integrates synthetic organic chemistry, computational chemistry and biological assays aimed at developing new chemotherapeutic entities. The current areas of research include:

  1. Development of cannabinoid receptor (CB1 and CB2) agonist and antagonist.
  2. Development of novel therapies for combat causality care with emphasis on hemorrhagic shock and hemostasis.
  3. Development of GPRC directed anti-neoplastic agents.
  4. Combination drug therapies for the treatment of sepsis, stroke and ischemic brain conditions.

Representative Publications

  • Moore BM, Adams JT, Barakatt E. Outcomes Following a Vestibular Rehabilitation and Aerobic Training Program to Address Persistent Post-Concussion Symptoms. J Allied Health. 2016 Winter;45(4):e59-e68. PubMed PMID: 27915363.
  • Cochran BJ, Hou L, Manavalan AP, Moore BM, Tabet F, Sultana A, Cuesta Torres L, Tang S, Shrestha S, Senanayake P, Patel M, Ryder WJ, Bongers A, Maraninchi M, Wasinger VC, Westerterp M, Tall AR, Barter PJ, Rye KA. Erratum. Impact of Perturbed Pancreatic β-Cell Cholesterol Homeostasis on Adipose Tissue and Skeletal Muscle Metabolism. Diabetes 2016;65:3610-3620. Diabetes. 2016 Dec 1. pii: db17er02b. [Epub ahead of print] PubMed PMID: 27908917.
  • Bu W, Ren H, Deng Y, Del Mar N, Guley NM, Moore BM, Honig MG, Reiner A. Mild Traumatic Brain Injury Produces Neuron Loss That Can Be Rescued by Modulating Microglial Activation Using a CB2 Receptor Inverse Agonist. Front Neurosci. 2016 Oct 6;10:449. PubMed PMID: 27766068; PubMed Central PMCID: PMC5052277.
  • Cochran BJ, Hou L, Manavalan AP, Moore BM, Tabet F, Sultana A, Cuesta Torres L, Tang S, Shrestha S, Senanayake P, Patel M, Ryder WJ, Bongers A, Maraninchi M, Wasinger VC, Westerterp M, Tall AR, Barter PJ, Rye KA. Impact of Perturbed Pancreatic β-Cell Cholesterol Homeostasis on Adipose Tissue and Skeletal Muscle Metabolism. Diabetes. 2016 Dec;65(12):3610-3620. Erratum in: Diabetes. 2016 Dec 1;:. PubMed PMID: 27702832; PubMed Central PMCID: PMC5132410.
  • Presley CS, Abidi AH, Moore BM 2nd. Optimization of cAMP fluorescence dataset from ACTOne cannabinoid receptor 1 cell line. Data Brief. 2016 Apr 1;7:1118-23. doi: 10.1016/j.dib.2016.03.086. PubMed PMID: 27115025; PubMed Central PMCID: PMC4833130.
  • Presley CS, Abidi AH, Moore BM 2nd. Corrigendum to 'Cannabinoid receptor 1 ligands revisited: Pharmacological assessment in the ACTOne system' [Analytical Biochemistry 498 (2016) 8-28]. Anal Biochem. 2016 May 15;501:47. doi: 10.1016/j.ab.2016.03.002. PubMed PMID: 27064120.

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