Bob M. Moore II, Ph.D.

Bob M. Moore II, Ph.D.

Professor


Department of Pharmaceutical Sciences


The University of Tennessee Health Science Center
874 Union Avenue, Room 327D
Memphis, TN 38163
Tel: (901) 448-6085
Fax: (508) 448-6828
Email: Bob M. Moore



Education

  • B.S. in Chemistry, Indiana State University, 1983
  • M.S. in Chemistry, Indiana State University, 1989
  • Ph.D. (Medicinal Chemistry), University of Kansas, 1995

Research Interests

Research in Dr. Moore's lab integrates synthetic organic chemistry, computational chemistry and biological assays aimed at developing new chemotherapeutic entities. The current areas of research include:

  1. Development of cannabinoid receptor (CB1 and CB2) agonist and antagonist.
  2. Development of novel therapies for combat causality care with emphasis on hemorrhagic shock and hemostasis.
  3. Development of GPRC directed anti-neoplastic agents.
  4. Combination drug therapies for the treatment of sepsis, stroke and ischemic brain conditions.

Representative Publications

  • Overman AE, Liu M, Kurachek SC, Shreve MR, Maynard RC, Mammel MC, Moore BM. Tracheostomy for infants requiring prolonged mechanical ventilation: 10 years' experience. Pediatrics. 2013 May;131(5):e1491-6. doi: 10.1542/peds.2012-1943. Epub 2013 Apr 8. PubMed PMID: 23569088.
  • Moore BM, Laguna TA, Liu M, McNamara JJ. Increased adherence to CFF practice guidelines for pulmonary medications correlates with improved FEV1. Pediatr Pulmonol. 2012 Sep 19. doi: 10.1002/ppul.22665. [Epub ahead of print] PubMed PMID: 22997186.
  • Gurley SN, Abidi AH, Allison P, Guan P, Duntsch C, Robertson JH, Kosanke SD, Keir ST, Bigner DD, Elberger AJ, Moore BM 2nd. Mechanism of anti-glioma activity and in vivo efficacy of the cannabinoid ligand KM-233. J Neurooncol. 2012 Nov;110(2):163-77. doi: 10.1007/s11060-012-0958-5. Epub 2012 Aug 9. PubMed PMID: 22875710.
  • Moore BM, Alex-Hart BA, George IO. Utilization of health care services by pregnant mothers during delivery: a community based study in Nigeria. East Afr J Public Health. 2011 Mar;8(1):49-51. PubMed PMID: 22066284.
  • Moore BM, Savdie R, PeBenito RA, Haynes AM, Matthews J, Delprado W, Rasiah KK, Stricker PD. The impact of nerve sparing on incidence and location of positive surgical margins in radical prostatectomy. BJU Int. 2012 Feb;109(4):533-8. doi: 10.1111/j.1464-410X.2011.10361.x. Epub 2011 Jun 28. PubMed PMID: 21711436.
  • Vaddady PK, Mehrotra N, Zhang X, Yates CR, Moore BM, Meibohm B. Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock. Biopharm Drug Dispos. 2011 Mar;32(2):89-98. doi: 10.1002/bdd.740. Epub 2010 Dec 23. PubMed PMID: 21341278.

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