Stanislav S. Zakharenko, M.D., Ph.D.

Stanislav S. Zakharenko, M.D., Ph.D.

Assistant Member
Department of Developmental Neurobiology
St. Jude Children's Research Hospital

Affiliated Associate Professor
Department of Anatomy and Neurobiology

St. Jude Children's Research Hospital
332 N. Lauderdale
Memphis, TN 38105-2794
Tel: (901) 595-3837
Fax: (901) 595-3143
Lab: MS 323, Room D2025B
Email: Stanislav S. Zakharenko


Research Interests

  • Functional organization and synaptic plasticity in the auditory cortex
  • Molecular and cellular mechanisms of cognitive deficits during schizophrenia
  • Synaptic plasticity in the hippocampus

Representative Publications

  • Chun S, Westmoreland JJ, Bayazitov IT, Eddins D, Pani AK, Smeyne RJ, Yu J, Blundon JA, Zakharenko SS. Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models. Science. 2014 Jun 6;344(6188):1178-82. doi: 10.1126/science.1253895. PubMed PMID: 24904170; PubMed Central PMCID: PMC4349506.
  • Earls LR, Westmoreland JJ, Zakharenko SS. Non-coding RNA regulation of synaptic plasticity and memory: implications for aging. Ageing Res Rev. 2014 Sep;17:34-42. doi: 10.1016/j.arr.2014.03.004. Epub 2014 Mar 27. Review. PubMed PMID: 24681292; PubMed Central PMCID: PMC4145026.
  • Bayazitov IT, Westmoreland JJ, Zakharenko SS. Forward suppression in the auditory cortex is caused by the Ca(v)3.1 calcium channel-mediated switch from bursting to tonic firing at thalamocortical projections. J Neurosci. 2013 Nov 27;33(48):18940-50. doi: 10.1523/JNEUROSCI.3335-13.2013. PubMed PMID: 24285899; PubMed Central PMCID: PMC3841456.
  • Earls LR, Zakharenko SS. A Synaptic Function Approach to Investigating Complex Psychiatric Diseases. Neuroscientist. 2013 Aug 1;20(3):257-271. [Epub ahead of print] Review. PubMed PMID: 23907185; PubMed Central PMCID: PMC4057991.
  • Chun S, Bayazitov IT, Blundon JA, Zakharenko SS. Thalamocortical long-term potentiation becomes gated after the early critical period in the auditory cortex. J Neurosci. 2013 Apr 24;33(17):7345-57. doi: 10.1523/JNEUROSCI.4500-12.2013. PubMed PMID: 23616541; PubMed Central PMCID: PMC3679664.
  • Blundon JA, Zakharenko SS. Presynaptic gating of postsynaptic synaptic plasticity: a plasticity filter in the adult auditory cortex. Neuroscientist. 2013 Oct;19(5):465-78. doi: 10.1177/1073858413482983. Epub 2013 Apr 4. Review. PubMed PMID: 23558179; PubMed Central PMCID: PMC4057285.

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