Stanislav S. Zakharenko, M.D., Ph.D.

Stanislav S. Zakharenko, M.D., Ph.D.

Associate Member
Department of Developmental Neurobiology
St. Jude Children's Research Hospital

Affiliate Associate Professor
Department of Anatomy and Neurobiology


St. Jude Children's Research Hospital
332 N. Lauderdale
Memphis, TN 38105-2794
Tel: (901) 595-3837
Fax: (901) 595-3143
Lab: MS 323, Room D2025B
Email: Stanislav S. Zakharenko

 

Link

Research Interests

  • Functional organization and synaptic plasticity in the auditory cortex
  • Molecular and cellular mechanisms of cognitive deficits during schizophrenia
  • Synaptic plasticity in the hippocampus

Representative Publications

  • Gingras S, Earls LR, Howell S, Smeyne RJ, Zakharenko SS, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015 Jul 22;35(29):10510-22. doi: 10.1523/JNEUROSCI.2056-14.2015. PubMed PMID: 26203146; PubMed Central PMCID: PMC4510291.
  • Chun S, Westmoreland JJ, Bayazitov IT, Eddins D, Pani AK, Smeyne RJ, Yu J, Blundon JA, Zakharenko SS. Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models. Science. 2014 Jun 6;344(6188):1178-82. doi: 10.1126/science.1253895. PubMed PMID: 24904170; PubMed Central PMCID: PMC4349506.
  • Earls LR, Westmoreland JJ, Zakharenko SS. Non-coding RNA regulation of synaptic plasticity and memory: implications for aging. Ageing Res Rev. 2014 Sep;17:34-42. doi: 10.1016/j.arr.2014.03.004. Epub 2014 Mar 27. Review. PubMed PMID: 24681292; PubMed Central PMCID: PMC4145026.
  • Bayazitov IT, Westmoreland JJ, Zakharenko SS. Forward suppression in the auditory cortex is caused by the Ca(v)3.1 calcium channel-mediated switch from bursting to tonic firing at thalamocortical projections. J Neurosci. 2013 Nov 27;33(48):18940-50. doi: 10.1523/JNEUROSCI.3335-13.2013. PubMed PMID: 24285899; PubMed Central PMCID: PMC3841456.
  • Earls LR, Zakharenko SS. A Synaptic Function Approach to Investigating Complex Psychiatric Diseases. Neuroscientist. 2013 Aug 1;20(3):257-271. [Epub ahead of print] Review. PubMed PMID: 23907185; PubMed Central PMCID: PMC4057991.
  • Chun S, Bayazitov IT, Blundon JA, Zakharenko SS. Thalamocortical long-term potentiation becomes gated after the early critical period in the auditory cortex. J Neurosci. 2013 Apr 24;33(17):7345-57. doi: 10.1523/JNEUROSCI.4500-12.2013. PubMed PMID: 23616541; PubMed Central PMCID: PMC3679664.

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