Michael R. Taylor, Ph.D.
Assistant Member
Department of Chemical Biology and Therapeutics
St. Jude Children's Research Hospital
Affiliated Assistant Professor
Department of Anatomy and Neurobiology
St. Jude Children's Research Hospital
262 Danny Thomas Place, MS-1000
Memphis, TN 38105-3678
Tel: (901) 595-6269
Email: Michael R. Taylor
Grants Quick Links
Education
- Ph.D. Institution: Department of Biochemistry, University of Washington, Seattle
- Postdoctoral: University of Washington; University of California, San Francisco
Link
St. Jude Faculty - Michael Taylor
Research Interests
- Establishing zebrafish as a model to study blood-brain barrier function and development.
- Characterizing and cloning zebrafish mutants with synaptic transmission defects.
- Developing high-throughput and high-content small-molecule screens aimed to identify biologically-active compounds.
Representative Publications
- Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, Zeng FY, Shelat AA, Guy K, Taylor MR, Chen T, Roussel MF. Identification of small molecule activators of BMP signaling. PLoS One. 2013;8(3):e59045. doi: 10.1371/journal.pone.0059045. Epub 2013 Mar 19. PubMed PMID: 23527084; PubMed Central PMCID: PMC3602516.
- Umans RA, Taylor MR. Zebrafish as a model to study drug transporters at the blood-brain barrier. Clin Pharmacol Ther. 2012 Nov;92(5):567-70. doi: 10.1038/clpt.2012.168. Epub 2012 Oct 10. PubMed PMID: 23047649.
- Lessman CA, Taylor MR, Orisme W, Carver EA. Use of flatbed transparency scanners in zebrafish research: versatile and economical adjuncts to traditional imaging tools for the Danio rerio laboratory. Methods Cell Biol. 2010;100:295-322. doi: 10.1016/B978-0-12-384892-5.00012-8. PubMed PMID: 21111223.
- Ju B, Spitsbergen J, Eden CJ, Taylor MR, Chen W. Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish. Mol Cancer. 2009 Jun 25;8:40. doi: 10.1186/1476-4598-8-40. PubMed PMID: 19555497; PubMed Central PMCID: PMC2711045.
- Nevin LM, Taylor MR, Baier H. Hardwiring of fine synaptic layers in the zebrafish visual pathway. Neural Dev. 2008 Dec 16;3:36. doi: 10.1186/1749-8104-3-36. PubMed PMID: 19087349; PubMed Central PMCID: PMC2647910.
- Baraban SC, Dinday MT, Castro PA, Chege S, Guyenet S, Taylor MR. A large-scale mutagenesis screen to identify seizure-resistant zebrafish. Epilepsia. 2007 Jun;48(6):1151-7. Epub 2007 May 23. PubMed PMID: 17521353; PubMed Central PMCID: PMC2211740.
