Alessandro Iannaccone, M.D., M.S.

Alessandro Iannaccone, M.D., M.S.

Retinal Degeneration & Ophthalmic Genetics Service
Lions Visual Function Diagnostic Lab

Associate Professor
Department of Ophthalmology
The University of Tennessee Health Science Center

The University of Tennessee Health Science Center
Hamilton Eye Institute
930 Madison Ave, Suite 731 (academic)
930 Madison Ave, Suite 400 (clinical)
Memphis, TN 38163 (USA)
Phone: (901) 448-7831 (academic)
(901) 448-6445/6185 (lab)
(901) 448-1241 (UTMG front desk)
Fax: (901) 448-5028 (UT)/1021 (UTMG)
Email: Alessandro Iannaccone


  • M.D. Institution: University La Sapienza, School of Medicine, Rome, Italy
  • M.S. Institution: (Epidemiology) College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, TN
  • Postdoctoral: (Medical Retina Research) Scheie Eye Institute, University of Pennsylvania, Philadelphia; (Pediatric Retinal and Optic Nerve Diseases) University of Tennessee Health Science Center, Memphis
  • Residency: School of Ophthalmology, Institute of Ophthalmology, University of Rome, Italy


Research Interests

Presently, stronger emphasis in my research is on 1) inflammatory and autoimmune aspects of age related macular degeneration and panretinal retinopathies; 2) hereditary retinal diseases such as X-linked and dominant retinitis pigmentosa (RP), Leber's congenital amaurosis, Usher syndrome (RP with hearing loss) and Bardet-Biedl syndrome (RP with obesity, polydactyly, and other systemic manifestations); and 3) nutritional influences on macular function and macular pigment.

Recent Publications

  • Mookherjee S, Chen HY, Isgrig K, Yu W, Hiriyanna S, Levron R, Li T, Colosi P, Chien W, Swaroop A, Wu Z. A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration. Cell Rep. 2018 Oct 16;25(3):611-623.e6. doi: 10.1016/j.celrep.2018.09.043. PubMed PMID: 30332642.
  • Larsen PS, Marino F, Melehan K, Guelfi KJ, Duffield R, Skein M. High-intensity interval exercise induces greater acute changes in sleep, appetite-related hormones and free-living energy intake compared to moderate-intensity continuous exercise. Appl Physiol Nutr Metab. 2018 Oct 17. doi: 10.1139/apnm-2018-0503. [Epub ahead of print] PubMed PMID: 30332549.
  • Fuller KA, Karunaratne NS, Naidu S, Exintaris B, Short JL, Wolcott MD, Singleton S, White PJ. Development of a self-report instrument for measuring in-class student engagement reveals that pretending to engage is a significant unrecognized problem. PLoS One. 2018 Oct 17;13(10):e0205828. doi: 10.1371/journal.pone.0205828. eCollection 2018. PubMed PMID: 30332460.
  • Zhang Y, Huang W. Transforming Growth Factor β1 (TGF-β1)-Stimulated Integrin-Linked Kinase (ILK) Regulates Migration and Epithelial-Mesenchymal Transition (EMT) of Human Lens Epithelial Cells via Nuclear Factor κB (NF-κB). Med Sci Monit. 2018 Oct 17;24:7424-7430. doi: 10.12659/MSM.910601. PubMed PMID: 30332398.
  • Dell'Osso LF, Orge FH, Jacobs JB, Wang ZI. Longitudinal Studies and Eye-Movement-Based Treatments of Infantile Nystagmus Syndrome: Estimated and Measured Therapeutic Improvements in Three Complex Cases. J Binocul Vis Ocul Motil. 2018 Oct 17:1-12. doi: 10.1080/2576117X.2018.1522917. [Epub ahead of print] PubMed PMID: 30332339.
  • Nanda KD, Blaha B, Churchfield WT, Fulwylie CR, Medsinge A, Nischal KK. Induced Tropia Test and Visual Acuity Testing in Nonverbal Children. J Binocul Vis Ocul Motil. 2018 Oct 17:1-3. doi: 10.1080/2576117X.2018.1525235. [Epub ahead of print] PubMed PMID: 30332333.

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