Alessandro Iannaccone, M.D., M.S.

Alessandro Iannaccone, M.D., M.S.

Retinal Degeneration & Ophthalmic Genetics Service
Lions Visual Function Diagnostic Lab

Associate Professor
Department of Ophthalmology
The University of Tennessee Health Science Center

The University of Tennessee Health Science Center
Hamilton Eye Institute
930 Madison Ave, Suite 731 (academic)
930 Madison Ave, Suite 400 (clinical)
Memphis, TN 38163 (USA)
Phone: (901) 448-7831 (academic)
(901) 448-6445/6185 (lab)
(901) 448-1241 (UTMG front desk)
Fax: (901) 448-5028 (UT)/1021 (UTMG)
Email: Alessandro Iannaccone


  • M.D. Institution: University La Sapienza, School of Medicine, Rome, Italy
  • M.S. Institution: (Epidemiology) College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, TN
  • Postdoctoral: (Medical Retina Research) Scheie Eye Institute, University of Pennsylvania, Philadelphia; (Pediatric Retinal and Optic Nerve Diseases) University of Tennessee Health Science Center, Memphis
  • Residency: School of Ophthalmology, Institute of Ophthalmology, University of Rome, Italy


Research Interests

Presently, stronger emphasis in my research is on 1) inflammatory and autoimmune aspects of age related macular degeneration and panretinal retinopathies; 2) hereditary retinal diseases such as X-linked and dominant retinitis pigmentosa (RP), Leber's congenital amaurosis, Usher syndrome (RP with hearing loss) and Bardet-Biedl syndrome (RP with obesity, polydactyly, and other systemic manifestations); and 3) nutritional influences on macular function and macular pigment.

Recent Publications

  • Sagiv O, Zloto O, Moroz I, Moisseiev J. Different Clinical Courses on Long-Term Follow-Up of Age-Related Macular Degeneration Patients Treated with Intravitreal Anti-Vascular Endothelial Growth Factor Injections. Ophthalmologica. 2017 Sep 20. doi: 10.1159/000479437. [Epub ahead of print] PubMed PMID: 28926846.
  • Chen TC, Yeh CY, Lin CW, Yang CM, Yang CH, Lin IH, Chen PY, Cheng JY, Hu FR. Vascular hypoperfusion in acute optic neuritis is a potentially new neurovascular model for demyelinating diseases. PLoS One. 2017 Sep 19;12(9):e0184927. doi: 10.1371/journal.pone.0184927. eCollection 2017. PubMed PMID: 28926646.
  • Chen FY, Lee A, Ge S, Nathan S, Knox SM, McNamara NA. Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome. PLoS One. 2017 Sep 19;12(9):e0184916. doi: 10.1371/journal.pone.0184916. eCollection 2017. PubMed PMID: 28926640.
  • Blanco MJ, Rodríguez-Martín I, Learte AIR, Clemente C, Montalvo MG, Seiki M, Arroyo AG, Sánchez-Camacho C. Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo. PLoS One. 2017 Sep 19;12(9):e0184767. doi: 10.1371/journal.pone.0184767. eCollection 2017. PubMed PMID: 28926609.
  • Seritrakul P, Gross JM. Tet-mediated DNA hydroxymethylation regulates retinal neurogenesis by modulating cell-extrinsic signaling pathways. PLoS Genet. 2017 Sep 19;13(9):e1006987. doi: 10.1371/journal.pgen.1006987. [Epub ahead of print] PubMed PMID: 28926578.
  • Naufel MF, Frange C, Andersen ML, Girão MJBC, Tufik S, Beraldi Ribeiro E, Hachul H. Association between obesity and sleep disorders in postmenopausal women. Menopause. 2017 Sep 18. doi: 10.1097/GME.0000000000000962. [Epub ahead of print] PubMed PMID: 28926516.

View more references (pubmed link)