Alessandro Iannaccone, M.D., M.S.

Alessandro Iannaccone, M.D., M.S.

Retinal Degeneration & Ophthalmic Genetics Service
Lions Visual Function Diagnostic Lab

Associate Professor
Department of Ophthalmology
The University of Tennessee Health Science Center

The University of Tennessee Health Science Center
Hamilton Eye Institute
930 Madison Ave, Suite 731 (academic)
930 Madison Ave, Suite 400 (clinical)
Memphis, TN 38163 (USA)
Phone: (901) 448-7831 (academic)
(901) 448-6445/6185 (lab)
(901) 448-1241 (UTMG front desk)
Fax: (901) 448-5028 (UT)/1021 (UTMG)
Email: Alessandro Iannaccone


  • M.D. Institution: University La Sapienza, School of Medicine, Rome, Italy
  • M.S. Institution: (Epidemiology) College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, TN
  • Postdoctoral: (Medical Retina Research) Scheie Eye Institute, University of Pennsylvania, Philadelphia; (Pediatric Retinal and Optic Nerve Diseases) University of Tennessee Health Science Center, Memphis
  • Residency: School of Ophthalmology, Institute of Ophthalmology, University of Rome, Italy


Research Interests

Presently, stronger emphasis in my research is on 1) inflammatory and autoimmune aspects of age related macular degeneration and panretinal retinopathies; 2) hereditary retinal diseases such as X-linked and dominant retinitis pigmentosa (RP), Leber's congenital amaurosis, Usher syndrome (RP with hearing loss) and Bardet-Biedl syndrome (RP with obesity, polydactyly, and other systemic manifestations); and 3) nutritional influences on macular function and macular pigment.

Recent Publications

  • Lužnik Z, Breda C, Barbaro V, Ferrari S, Migliorati A, Di Iorio E, Ferrari B, Griffoni C, Grassetto A, Elbadawy HM, Bertolin M. Towards xeno-free cultures of human limbal stem cells for ocular surface reconstruction. Cell Tissue Bank. 2017 May 26. doi: 10.1007/s10561-017-9632-7. [Epub ahead of print] PubMed PMID: 28550448.
  • Cole TJ, Young M. Mineralocorticoid receptor null mice: informing cell type-specific roles. J Endocrinol. 2017 May 26. pii: JOE-17-0155. doi: 10.1530/JOE-17-0155. [Epub ahead of print] PubMed PMID: 28550025.
  • Regmi SC, Samsom ML, Heynen M, Jay GD, Sullivan BD, Srinivasan S, Caffery B, Jones L, Schmidt TA. Degradation of proteoglycan 4/lubricin by cathepsin S: Potential mechanism for diminished ocular surface lubrication in Sjögren's syndrome. Exp Eye Res. 2017 May 23. pii: S0014-4835(17)30373-1. doi: 10.1016/j.exer.2017.05.006. [Epub ahead of print] PubMed PMID: 28549901.
  • Igić R. Four decades of ocular renin-angiotensin and kallikrein-kinin systems (1977-2017). Exp Eye Res. 2017 May 23. pii: S0014-4835(17)30179-3. doi: 10.1016/j.exer.2017.05.007. [Epub ahead of print] Review. PubMed PMID: 28549900.
  • Zhao D, Guallar E, Gajwani P, Swenor B, Crews J, Saaddine J, Mudie L, Varadaraj V, Friedman DS; SToP Glaucoma Study Group.. Optimizing glaucoma screening in high risk population: design and 1-year findings of the Screening to Prevent (SToP) Glaucoma study. Am J Ophthalmol. 2017 May 23. pii: S0002-9394(17)30219-2. doi: 10.1016/j.ajo.2017.05.017. [Epub ahead of print] PubMed PMID: 28549849.
  • Ou WC, Brown DM, Payne JF, Wykoff CC. Relationship Between Visual Acuity and Retinal Thickness During Anti-Vascular Endothelial Growth Factor Therapy for Retinal Diseases. Am J Ophthalmol. 2017 May 23. pii: S0002-9394(17)30216-7. doi: 10.1016/j.ajo.2017.05.014. [Epub ahead of print] PubMed PMID: 28549848.

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