Research Interests: The mechanisms that regulate vascular reactivity in physiological and pathophysiological conditions.

Research Interests: Animal models for neurodegeneration disorders: Huntington's disease.

Research Interests: To understand the structure and function of ion channels. One specific area is to study inwardly rectifying potassium channels.

Research Interests: Second messenger signaling pathways in the heart.

Research Interests: Regulation of arterial smooth muscle function by calcium signaling and ion channels.

Research Interests: The role of polyamines in growth, migration and death of intestinal epithelial cells.

Research Interests: Autocrine/paracrine control of the newborn cerebral circulation, and the cellular mechanisms involved in such control.

Research Interests: Structure and function of ion channels with special emphasis on CFTR

Research Interests: Understanding the mechanisms that underlie the specific distribution of Kv channels and how channel localization affects electrical signaling.

Research Interests: We investigate the roles of heme oxygenase and carbon monoxide, the heme oxygenase derived endogenous gaseous mediator in regulating blood flow to the brain and in promoting survival of brain endothelial cells during cerebral vascular insult caused by seizures and oxidative stress.

Research Interests: Inflammatory responses in lung microcirculation; Role of junctional proteins as mediators of proinflammatory signaling.

Research Interests: Gene regulation, cell signaling and vascular wall remodeling; Phospholipases, eicosanoids, cytokines and endothelial cell barrier function and pathological angiogenesis

Research Interests: Regulation of epithelial tight junctions and adherens junctions by intracellular signal transduction with special emphasis on protein phosphorylation.

Research Interests: Gene therapy for blood and immune system disorders using safety modified lentiviral vectors. I also have a more basic program on the effects of transcription factors on hematopoietic stem cell biology and T cell leukemia.

Research Interests: Mechanisms controlling potassium content and volume of muscle

Research Interests: Lipid growth factors in health and disease with a particular emphasis on drug discovery of anti-metastatic lipids. We are particularly interested in developing radiomitigators that protect animals from lethal levels of irradiation.

Research Interests: Acute lung injury; Mechanotransduction; Epithelial wound healing; Cellular biomechanics and transport; Ventilator-induced lung injury; Asthma; Vascular endothelial and lung epithelial cell barrier function and the effects of mechanical stresses.

Research Interests: Ion channels and cell behavior during wound healing.

Research Interests: My lab is studying the role of microRNA gene in vascular disease using replication defective viral vectors, transgenic/knockout mouse and rat models.