BioImaging

Current research concentrations include:

  • Variable Resolution Computed Tomography
  • Functional Neuroimaging
  • Molecular Imaging
  • Digital Projection Radiography
  • Quantitative Ultrasound Imaging
  • Image Processing and Reconstruction Algorithms
  • Cone Beam Computed Tomography
  • Optical Imaging
  • Radiotherapy Imaging

Some examples of specific on-going projects are described below:

VRX CT Scanner

VRX CT Scanner

A novel x-ray detector for CT scanning is being developed and evaluated, having a Variable Resolution X-ray (VRX) geometry that boosts resolution by scaling the detector cell array to the size of the subject being scanned.


Functional Neuroimaging

Functional Neuroimaging

Functional neuroimaging technology is being used to investigate the impact of disease and treatment on brain function among children with catastrophic diseases. Diffusion tensor imaging (DTI) shows major white matter pathways in the brain. The multicolor images at the left illustrate normal white matter anatomy with red-green-blue encoding of the x-y-z orientation of the fibers.


Molecular Imaging

Molecular Imaging

Non-invasive imaging techniques such as X-ray, CT, intravital microscopy, near infrared and fluorescence are developed and used to study radiation effects on the blood-brain barrier, CNS tumors and novel drug delivery methods.


Data Pre-processing for VRX Scanners

Data Pre-processing for VRX Scanners

The purpose of this research is to address some of the unique data processing challenged faced in optimizing the performance of Variable Resolution X-ray detectors used as CT scanners.


Automatic Brain Tumor Detection in
Magnetic Resonance Imaging (MRI)

Automatic Brain Tumor Detection in Magnetic Resonance Imaging (MRI)

An automatic method to detect the tumor region in the brain using MRI images is being developed. The algorithm incorporates steps of feature extraction, image segmentation and image classification using fractal wavelet, image fusion, and neural network techniques.


Vein Contrast Enhancement

Vein Contrast Enhancement

An optical imaging device has been developed that acquires an image of veins using near infrared light and projects an enhanced version of that image back onto the patient in real time using green light.


Digital Projection Radiography

Digital Projection Radiography

Digital Projection Radiography addresses the replacement of conventional film/screen radiography by digital equipment and techniques to provide improved image quality, better patient care and increased productivity. Specific areas of development include computed radiography and digital radiography systems, flat panel detectors, high performance photostimulable phosphor screens, and image processing.


Quantitative Ultrasound Imaging

The goal of this research is to develop tissue classification aids based on objective criteria such as stiffness, concentration, size and attenuation. A standard B-mode thyroid image (C) has been analyzed to illustrate scatterer radius (A), scatterer size (D), and tissue stiffness (B).

Quantitative Ultrasound Imaging
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Biomedical Engineering

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