Hypertension Research Day Previous Seminars

1990

E. Eric Muirhead, M.D., Professor, Department of Pathology,University of Tennessee, Memphis
Medullipin System of Blood Pressure Control

Ben F. Zimmerman, Ph.D., Professor of Pharmacology, University of Minnesota
A Search for the Functional Role of the Local Renin-Angiotensin System

Leonard Share, Ph.D., Professor, Department of Physiology, University of Tennessee, Memphis
Brain Prostaglandins and the Control of Vasopressin Release

Allyn Mark, M.D.,Leonard Share Distinguished Visiting Professor, Professor of Medicine, Director, Cardiovascular Division, Editor-in-Chief, “Hypertension”, University of Iowa
Mild Hypertension: New Insights from Direct Recordings of Sympathetic Nerve Activity in Humans

1991

C. Robert Cooke, M.D., Professor of Medicine, Chief, Department of Nephrology Section, Veterans Administration Medical Center, Memphis
Non-osmotic Control of Vasopressin Release in Man

Alberto Nasjletti, M.D., Professor of Pharmacology, New York Medical College
Role of Prostanoid-Mediated Mechanisms of Vascular Contraction in Renin-Dependent Hypertension

Allen W. Cowley, Jr., Ph.D., Professor and Chairman, Department of Physiology, Medical College of Wisconsin
Pathways Linking Renal Excretion and Arterial Pressure

Donald J. Reis, M.D., Leonard Share Distinguished Visiting Professor, George C. Cotzias Distinguished, Professor of Neurology, Chief, Division of Neurobiology, Cornell University Medical College
Control by the Brainstem of the Systemic and Cerebral Circulation

1992

Aram V. Chobanian, M.D., Leonard Share Distinguished Visiting Professor, Dean and Professor of Medicine, Boston University School of Medicine
Responses of the Arterial Wall to Hypertension and Its Therapy

Kathleen H. Berecek, Ph.D., Professor, Physiology and Biophysics, Associate Scientist, Vascular Biology and Hypertension Program, University of Alabama at Birmingham
The Importance of the Brain Renin-Angiotensin II System in the Pathogenesis of Genetic Hypertension

Charles W. Leffler, Ph.D., Professor of Physiology/Biophysics and Pediatrics, Director, Laboratory for Research in Neonatal Physiology, University of Tennessee, Memphis
Prostacyclin as an Endothelially Derived Vasodilator in the Newborn Cerebral Circulation

Ray W. Gifford, Jr., M.D., Senior Vice Chairman, Division of Medicine, Acting Chairman, Department of Hypertension and Nephrology, Cleveland Clinic Foundation
Hypertension in the Elderly

1993

Stephen M. Schwartz, M.D., Ph.D., Leonard Share Distinguished Visiting Professor, Professor of Pathology, Department of Pathology, University of Washington
Smooth Muscle Diversity

Janice G. Douglas, M.D., Professor of Medicine, Director, Division of Endocrinology and Hypertension School of Medicine, Case Western Reserve University
Novel Aspects of Renal Angiotensin Receptors and Signaling

Aviv I. Hassid, Ph.D., Bronstein Professor of Cardiovascular Physiology, Department of Physiology and Biophysics, University of Tennessee, Memphis
Influence of Vasodilators and Cytokines on Vascular Smooth Muscle Growth

William C. Cushman, B.A., M.D., Associate Professor of Medicine and Preventive Medicine, College of Medicine, University of Tennessee, Memphis, Chief, Hypertension Section, Veterans Administration Medical Center
Is there a Correct Drug for Each Patient with Hypertension?

Edward D. Frohlich, M.D., Vice President for Academic Affairs, Alton Ochsner Medical Foundation
Left Ventricle Hypertrophy: A new Look

1994

John Rapp, D.V.M., Ph.D., Professor and Chairman Physiology and Molecular Medicine, Medical College of Ohio
The Molecular Genetic Analysis of Hypertension in the Rat

Donald B. Thomason, Ph.D., Assistant Professor, Department of Physiology, The University of Tennessee, Memphis
Response of Cardiac Gene Expression to Volume and Pressure Challenge

Thomas G. Pickering, M.D., D.Phil., Professor of Medicine, Hypertension Center, The New York Hospital, Cornell Medical Center
The Role of Behavioral Factors in the Development of Human Hypertension

Polly Hoffman, Ph.D., Assistant Professor, Department of Physiology, The University of Tennessee, Memphis
Mechanisms of Hormonal Regulation of Cardiac Contraction

Barry M. Brenner, M.D., Leonard Share Distinguished Visiting Professor, Director, Renal Division, Brigham and Women’s Hospital, Samuel A. Levine Professor of Medicine, Harvard Medical School
Nephrons and Kidneys: How Many are Enough?

1995

Theodore W. Kurtz, M.D., Professor, Laboratory Medicine, Chief, Clinical Chemistry, Moffit-Long Hospitals, University of California at San Francisco Medical Center
Genetics of Experimental Hypertension

Murray Heimberg, Ph.D., M.D., Van Fleet Professor, Chair, Pharmacology, Professor of Medicine, Endocrinology, and Metabolism, The University of Tennessee, Memphis
Regulation of VLDL Secretion, and Relationship to Atherogenesis

Juan Carlos Romero, M.D., Professor, Physiology and Biophysics, Mayo Clinic
The Use of Three Dimensional Computerized Tomography to Evaluate Renal Function

Victor J. Dzau, M.D., Leonard Share Distinguished Visiting Professor, Arthur L. Bloomfield Professor of Medicine, Chairman, Department of Medicine, Chief, Division of Cardiovascular Medicine, Stanford University School of Medicine
Gene Targeting and Gene Therapy in Hypertension and Vascular Research

Hiroko Nishimura, M.D., D.M.Sc., Professor, Department of Physiology, The University of Tennessee, Memphis
Vascular Endothelium – Smooth Muscle Interaction in Normal and Atherogenic Vessels

1996

Steven L. Bealer, Ph.D., Professor, Department of Physiology, The University of Tennessee, Memphis,
Hypothalamic Control of Heart Rate

David F. Bohr, M.D., Professor Emeritus of Physiology, University of Michigan, Ann Arbor, Michigan
Hypertension: A Role for Brain Nitric Oxide

Robert M. Carey, M.D., Dean and James Carroll Flippin Professor of Medical Sciences, University of Virginia Health Sciences Center – School of Medicine, Charlottesville, Virginia
The Role of the Angiotensin AT-2 Receptor in the Kidney

Oliver Smithies, D. Phil., Leonard Share Distinguished Visiting Professor, Excellence Professor of Pathology,, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Gene Targeting for Studying Hypertension

1997

Jay Sullivan, M.D., Professor of Medicine, Chief, Division of Cardiovascular Diseases, University of Tennessee, Memphis
Sodium Sensitivity: Long Term Aspects

James R. Sowers, M.D., Professor of Medicine and Physiology, Director of Endocrinology, Metabolism, and Hypertension, Wayne State University, Detroit, Michigan
Diabetes and Cardiovascular Disease

Oscar A. Carretero, M.D., Division Head, Hypertension & Vascular Research Division, Case Western Reserve University, Bloomfield Hills, Michigan
ACE Inhibitors and AT, Antagomsits: Similarities and Differences

Richard P. Lifton, M.D., Ph.D., Leonard Share Distinguished Visiting Professor, Professor of Medicine, Genetics, Molecular Biophysics, and Biochemistry, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut
Molecular Genetics of Human Blood Pressure Variation

1998

Michael L. Tuck, M.D., Department of Medicine Grand Rounds, Professor of Medicine, University of California School of Medicine, Los Angeles, California
Obesity and Hypertensio 

Bradford C. Berk, M.D., Ph.D., Director, Cardiovascular Research Center, University of Rochester Medical Center, Rochester, New York
Kinases thet Phosphorylate the Na+/H+ Exchanger (NHE-1); Candidate Hypertensive Mediators

Leonard Share, Ph.D., Professor, Department of Physiology, University of Tennessee, Memphis
Sexual Dimorphism in Cardiovascular Regulation

Michael J. Dunn, M.D., Leonard Share Distinguished Visiting Professor, Dean and Executive Vice President, Medical College of Wisconsin, Milwaukee, Wisconsin
Endothelin Signal Transduction: The Roles of Adapter Proteins, Ras, and Mitogen-Activated Protein Kinase Cascades

1999

Gordon Williams, M.D., Department of Medicine Grand Rounds, Chief, Endocrinology-Hypertension Division, Professor of Medicine, Brigham and Women’s Hospital Harvard Medical School, Boston, Massachusetts
How Genetics and Pathophysiologic Research Lead to Better Diagnosis and Treatment of Hypertension

Donald E. Ingber, M.D., Ph.D., Leonard Share Distinguished Visiting Professor, Professor, Department of Pathology, Children’s Hospital – Harvard Medical School, Boston, Massachusetts
Cellular Tensegrity and Mechanotransduction

Abraham Aviv, M.D., Professor and Director Hypertension Research Center, UMDNJ-New Jersey Medical School, Newark, New Jersey
Biological Clocks: Do They Play a Role in Essential Hypertension and Cardiovascular Diseases?

Barry Wall, M.D., Associate Professor, Department of Medicine-Nephrology, Veterans Administration Medical Center, University of Tennessee, Memphis
Cardiovascular Effects of Vasopressin in Humans

2000

Paul K. Whelton, M.D., M.Sc., Senior Vice President for Health, Tulane University Health Sciences Center, Acting Dean, Tulane University School of Medicine Sciences, New Orleans, Louisiana
Prevention and Treatment of Blood Pressure-Related Cardiovascular Disease

Edward D. Frohlich, M.D., Jay Sullivan Memorial Lectureship, Alton Ochsner Distinguished Scientist, Alton Ochsner Medical Foundation, New Orleans, Louisiana
2000: Current Concepts on the Heart in Hypertension

Donald D. Heistad, M.D., 2000 Leonard Share Distinguished Visiting Professor, Zahn Professor of internal Medicine and Pharmacology, Director of Cardiovascular Division, University of Iowa, Iowa City, Iowa
Vascular Gene Transfer and Gene Therapy

M. Ian Phillips, Ph.D., D.Sc., Professor and Chairman, Director of Hypertension Center, University of Florida, Gainesville, Florida
Gene Therapy for Hypertension: Viral or Non-Viral Antisens 

2001

Karl T. Weber, M.D., Jay M. Sullivan Memorial Lectureship, Professor of Medicine, Chief, Division of Cardiovascular Diseases, Stern Endowed Professor, University of Tennessee, Memphis
Hypertensive Heart Disease: What, Why, and How

Robert M. Carey, M.D., Leonard Share Distinguished Visiting Professor, Professor of Medicine and Dean, University of Virginia School of Medicine, Charlottesville, Virginia
AT2  Receptor Mechanisms in Cardiovascular and Renal Function

Joey P. Granger, Ph.D., Professor of Physiology and Medicine, University of Mississippi Medical Center, Jackson, Mississippi
Pregnancy-Induced Hypertension: Linking Placental Ischemia with Endothelial Dysfunction

Kafait U. Malik, Ph.D., D.Sc., Professor of Pharmacology, University of Tennessee, Memphis
Contribution of Eicosanoids to Vascular Smooth Muscle Cell Signaling, Hyperplasia and Hypertrophy and Hypertension

2002

Laurence Agodoa, M.D.,Grand Rounds, Director, Office of Minority Health Research Coordination, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
Hypertension and kidney diseases in African-American populations

Suzanne Oparil, M.D., Lenard Share Distinguished Visiting Professorship Lecture, Professor of Medicine and Director, Vascular Biology and Hypertension Program, University of Alabama
Sodium-sensitive hypertension:  Recent advances

Howard J. Jacob, Ph.D., Guest Speaker, Associate Professor, Department of Physiology
Implementation of genomic tools in cardiovascalar diseases

Bruce Alpert, M.D. , Local Speaker, Plough Foundation Professor Pediatrics, The University of Tennessee HSC
Hypertension prevention in minorities

2003

Jackson T. Wright, Jr., M.D., Ph.D., Medicine Grand Rounds, Stanford Moore Professor of Biochemistry and Professor of Medicine, Vanderbilt University School of Medicine
Angiotensin II receptors in cardiac hypertrophy

Tadashi Inagami, Ph.D., D.Sc., Leonard Share Distinguished Visiting Professor, Professor, Department of Medicine, Division of cardiology, Emory University
Hypertension and oxidative stress

Michael S. Wolin, Ph.D., Guest Speaker, Professor, Department of Physiology, New York Medical College
Oxidant signaling and the regulation of vascular function

Jonathan H. Jaggar, Ph.D. , Local Speaker, Assistant Professor, Department of Physiology, The University of Tennessee HSC
Calcium signaling in arterial smooth muscle

2004

John E. Hall, Ph.D., Medicine Grand Rounds, Professor and Chairman, Department of Physiology & Biophysics, University of Mississippi Medical Center
Mechanisms of hypertension and renal disease in the metabolic/obesity syndrome

Brian R. Duling, Ph.D., Leonard Share Distinguished Visiting Professor, Professor, Department of Molecular Physiology and Biophysics, Cardiovascular Research Center, University of Virginia Health Science Center
Endothelial gap junctions, connexins, and vascular  tone:  possible roles in hypertension

R. Clinton Webb, Ph.D., Hypertension Research Day Lecture  , Greenblatt Professor and Chairman, Department of Physiology, Medical College of Georgia
Integration of sympathetic neural control and pro-inflammatory mediators in hypertension

Pedro Velasquez, M.D. , Local Speaker, Assistant  Professor,, Department of Pediatrics, 4th floor, Le Bonheur Children's Medical Center UTHSC
Obesity, diabetes and hypertension in youth:  The new epidemic

2005

George L. Bakris, M.D. , Medicine Grand Rounds, Professor and Vice Chairman, Department of Preventive Medicine, Professor of Medicine, Rush-Presbyterian-St.Luke's Medical Center, Rush Medical College
Hypertension and kidney disease progression

Allen W. Cowley, Jr., Ph.D. , Leonard Share Distinguished Visiting Professor, Professor and Chairman, Department of Physiology, Medical College of Wisconsin
Arterial blood pressure regulation and hypertension:  Physiological mechanisms and genetic determinants

Christopher S. Wilcox, M.D., Ph.D., , Hypertension Research Day Lecture  , Chief and Professor of Nephrology, Chair, Georgetown University Center for Hypertension and Renal Disease Research, Georgetown University Medical Center
The pathogenesis of hypertension:  roles of oxidative stress and nitric oxide deficiency

William C. Cushman, M.D. , Local Speaker, Professor of Preventive Medicine and Medicine, The University of Tennessee HSC, Chief, Preventive Medicine Section, Veterans Affairs Medical Center, V.A. Medical Center, Hypertension Unit
An ALLHAT update:  What has ALLHAT taught us about the management of hypertension

2006

Hanna E. Abboud, M.D., Medicine Grand Rounds, Jay H. Stein Professor of Medicine, Director, Division of Nephrology, University of Texas Health Science Center, San Antonio, Texas
Pathogenic Mechanisms of Diabetic Nephropathy

Shu Chien, M.D., Ph.D., Leonard Share Distinguished Visiting Professor, Professor of Bioengineering and Medicine, Director, Whittaker Institute for Biomedical Engineering, University of California, San Diego, La Jolla, CA
Mechanotransduction of Endothelial Cells: Implication to Atherosclerosis and Hypertension

Richard Cohen, M.D., Eric Muirhead Hypertension Research Day Lecture, Jay and Louise Coffman Professor of Vascular Medicine, Professor of Medicine, Physiology, and Pharmacology, Department of Medicine, Director, Vascular Biology Unit, Boston University, Boston, MA
The Role of Nitric Oxide and Reactive Nitrogen Species in Vascular Cell Signaling and Disease

Yao Sun, M.D., Ph.D., Local Speaker, Professor of Medicine, Department of Medicine, Cardiology, University of Tennessee Health Science Center, Memphis, TN
Reactive Oxygen Species and Cardiac Remodeling

2007

David A. Calhoun, M.D., Associate Professor of Medicine, Division of Cardiovascular Disease, University of Alabama at Birmingham
Role of Aldosterone in Clinical Hypertension

Julie R. Ingelfinger, M.D., Professor of Pediatrics, Harvard Medical School
Clinical and Experimental Hypertension: Role of Development

Costantino Iadecola, M.D., George C. Cotzias Distinguished Professor of Neurology and Neuroscience, Weill Medical College of Cornell University
Hypertension as a Risk Factor for Stroke

Marshall B. Elam, M.D., Ph.D., Professor, Departments of Pharmacology and Medicine, University of Tennessee Health Science Center
Molecular Mechanisms by which Insulin Enhances Lipogenesis via Sterol Regulatory Element Binding Protein 1c: Regulation of the Regulator

2008

Ernesto L. Schiffrin M.D., Ph.D., FRSC, FRCPC, FACP, Medicine Grand Rounds, Physician-in-Chief and Chair, Department of Medicine, Sir Mortimer B. Davis-Jewish General Hospital, Canada Research Chair and Director, Hypertension and Vascular Research Unit, Lady Davis Institute for Medical Research,Professor and Vice-Chair (Research), Department of Medicine, McGill University
Inflammation in Hypertension

Nancy J. Rusch, Ph.D., Leondard Share Distinguished Visiting Professor, Professor and Chair, Department of Pharmacology & Toxicology, University of Arkansas for Medical Science
Long-Acting Gene Therapy for Hypertension: Targeted Delivery of a Potassium Channel Gene to the Vasculature

Thomas M. Coffman, M.D., Eric Muirhead Hypertension Research Day Lecture, James R. Clapp Professor of Medicine, Professor of Cell Biology and Immunology, Chief, Division of Nephrology, Duke University Medical Center
The Kidney in Hypertension: Guyton Redux

Alejandro M. Dopico, M.D., Ph.D., Local Speaker, Associate Professor of Pharmacology, The University of Tennessee Health Science Center
Non genomic modulation of vascular smooth muscle BK channels by physiologically relevant steroids

2009

Daniel Levy, M.D., FACC, Medicine Grand Rounds, Boston, MA
Hypertension 2009: Lessons from observational studies and clinical trials to guide patient care

Mordecai Blaustein, M.D., Leondard Share Distinguished Visiting Professor, Professor of Physiology & Medicine, Director, Maryland Center for Heart, Hypertension & Kidney Disease, University of Maryland, Baltimore
The (Blood) Pressure's on Salt! But, how does salt do it

Carlos Ferrario, M.D., Eric Muirhead Hypertension Research Day Lecture, Professor Hypertension and Vascular Research Center, Wake Forest University School of Medicine
Angiotensin-(1-12) and Angiotensin-(1-7) Reveal Complex Regulation of Renin Angiotensin System Mechanisms of Action

Guy Reed, M.S., M.D., University of Tennessee Health Science Center Lecture, Diggs Professor and Chair, Department of Medicine University of Tennessee Health Science Center
Natriuretic Peptide System in Heart Failure and Myocardial Infarction

2010

Nancy J. Brown, M.D., Hugh Jackson Morgan Professor of Medicine and Pharmacology, Chair and Physician-in-Chief, Department of Medicine, Vanderbilt University School of Medicine
A New Life for Mineralocorticoid Receptor Blockers

Theodore W. Kurtz, M.D., Professor and Vice Chair of Laboratory Medicine, Chief of Clinical Chemistry,
University of California San Francisco
Molecular Genetics and Therapeutics of the Metabolic Syndrome

Gregory D. Fink, Ph.D., Professor of Pharmacology and Toxicology, Michigan State University
Body Fluid Volume and its Distribution: Old and New Ideas on the Pathophysiology of Hypertension

Kafait U. Malik, Ph.D., D.Sc., Professor of Pharmacology, The University of Tennessee Health Science Center
Contribution of Cytochrome P450 1B1 to Hypertension and Associated Pathophysiology: A possible Target for Novel Antihypertensive Agents

2011

Jackson Wright, M.D.
Medicine Grand Rounds
Vice Chair, ALLHAT Steering Committee, Professor of Medicine Case Western Reserve University, Director, Clinical Hypertension Program, University Hospitals of Cleveland and the Louis Stokes Cleveland Veterans Affairs Medical Center.
Racial differences in hypertension management – how much is real?

Francois Abboud M.D.
Leonard Share Memorial Lecture
Edith King Pearson Chair in Cardiovascular Research, Professor of Medicine and Molecular Physiology and Biophysics, Director, Cardiovascular Research Center, Associate Vice President for Research, University of Iowa
Baroreceptors in Hypertension (Molecules and Function)

Neil Granger Ph.D.
Eric Muirhead Hypertension Research Day Lecture
Boyd Professor and Head, Department of Molecular and Cellular Physiology, Louisiana State University Medical Center.
Microvascular Responses to Risk Factors for Cardiovascular Disease

Robert Wyatt, M.D.
Local Speaker
Professor, Departments of Pediatrics and Preventive Medicine
University of Tennessee Health Science Center
IgA nephropathy - pathogenic mechanisms for the most common chronic glomerular disease

2012

John A. Oates, M.D.
Medicine Grand Rounds
Thomas F. Frist, Sr. Professor of Medicine & Professor of Pharmacology
Vanderbilt University Medical Center
Thrombotic Consequences of Metabolic Syndrome

Jane F. Reckelhoff, Ph.D.
Leonard Share Memorial Lecture
Billy S. Guyton Distinguished Professor, Director – Women's Health Research Center
University of Mississippi Medical Center
Sex Differences in Control of Blood Pressure

Curt D. Sigmund, Ph.D.
Eric Muirhead Hypertension Research Day Lecture
Roy J. Carver Chair in Hypertension Research, Professor and Head, Department of Pharmacology
Roy J. and Lucille A. Carver College of Medicine
University of Iowa
Identification of Cullin-3 as a Regulator of Vascular Function and Arterial Pressure

Sam Dagogo-Jack, M.D.
Local Speaker
Mullins Professor & Director, Division of Endocrinology, Diabetes & Metabolism
University of Tennessee Health Science Center
Synchronicity of Prehypertension and Prediabetes - Data from a Memphis Biracial Cohort

 

2013

Raymond R. Townsend, M.D.
Medicine Grand Rounds
Professor of Medicine
University of Pennsylvania Health System
Arterial stiffness – what does it add when I already know the blood pressure?

Rui Wang, M.D., Ph.D.
Leonard Share Memorial Lecture
Vice President of Research, Economic Development and Innovation
Lakehead University
Discovery of hydrogen sulfide as a gasotransmitter in the cardiovascular system

Csaba P. Kovesdy, M.D.
Eric Muirhead Hypertension Research Day Lecture
The Fred Hatch Professor of Medicine
Director, Clinical Outcomes and Clinical Trials Program in Nephrology
University of Tennessee Health Science Center
Hypertension treatment guidelines in patients with chronic kidney disease: Is it appropriate to extrapolate from the general population?

Kafait U. Malik, D.Sc., Ph.D.
University of Tennessee Health Science Center Lecture
Professor of Pharmacology
University of Tennessee Health Science Center
Molecular Mechanism Involved in Sex Differences in Angiotensin II-induced Hypertension

2014

Vito M. Campese, M.D.
Medicine Grand Rounds
Professor of Medicine
Division Chief, Department of Nephrology
Keck School of Medicine
University of Southern California
Renal Nerves in Hypertension

Pedro A. Jose, M.D., Ph.D.
Leonard Share Memorial Lecture
Professor of Medicine and Physiology
University of Maryland School of Medicine
Gastro-renal Communication and Sodium Excretion

L. Gabriel Navar, Ph.D.
E. Eric Muirhead Hypertension Research Day Lecture
Professor and Chair
Department of Physiology
Tulane University
Activation of the Intrarenal/Intratubular Renin Angiotensin System in Hypertension: Experimental and Translational Studies

Elvira O. Gosmanova, M.D.
University of Tennessee Health Science Center Lecture
Associate Professor
Department of Medicine – Division of Nephrology
University of Tennessee Health Science Center
Role of Adherence to Antihypertensive Medications in the Treatment of Hypertension: Is Prescribing the Right Pill Enough?

logo image

Wednesday, November 18

E.P. and Kate Coleman North Auditorium
A117 Coleman Building
956 Court Avenue
Memphis, TN 38163 Map